Evidence map›Paper›PMID 37959736›Full record

ArticleMolecules (Basel, Switzerland)2023

María Jesús Vega-Bello, Mari Luz Moreno, Rossana Estellés-Leal, José Miguel Hernández-Andreu, Jesús A Prieto-Ruiz

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. Usnic Acid and Its Topical Use-A Concise Review.Molecules (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Unassuming Lichens: Nature's Hidden Antimicrobial Warriors.International journal of molecular sciences · 2025
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

María Jesús Vega-BelloDepartment of Basic Biomedical Sciences, Catholic University of Valencia "San Vicente Mártir", C/Quevedo 2, 46001 Valencia, Spain.
Mari Luz MorenoDepartment of Anatomy and Physiology, Catholic University of Valencia "San Vicente Mártir", C/Quevedo 2, 46001 Valencia, Spain.ORCID 0000-0002-2471-0862
Rossana Estellés-LealDepartment of Basic Biomedical Sciences, Catholic University of Valencia "San Vicente Mártir", C/Quevedo 2, 46001 Valencia, Spain.
José Miguel Hernández-AndreuDepartment of Basic Biomedical Sciences, Catholic University of Valencia "San Vicente Mártir", C/Quevedo 2, 46001 Valencia, Spain.ORCID 0000-0002-2459-9754
Jesús A Prieto-RuizDepartment of Basic Biomedical Sciences, Catholic University of Valencia "San Vicente Mártir", C/Quevedo 2, 46001 Valencia, Spain.ORCID 0000-0003-2726-7963
Universitat de València · ES

Funding

Valencia Catholic University Saint Vincent Martyr 2011-011-012
6 · The paper itself

Abstract

backgroundLichens are complex symbiotic associations between a fungus and an alga or cyanobacterium. Due to their great adaptability to the environment, they have managed to colonize many terrestrial habitats, presenting a worldwide distribution from the poles to the tropical regions and from the plains to the highest mountains. In the flora of the Antarctic region, lichens stand out due to their variety and development and are a potential source of new bioactive compounds.

methodsA phytochemical study of the Antarctic lichen

resultsCytotoxicity studies revealed that the hexane extract contains usnic acid as a majority metabolite, in addition to linoleic acid, ergosterols and terpenes, and demonstrates cytotoxic activity against an A375 melanoma cell line. On the other hand, the presence of total phenols in the extracts did not influence their antioxidant activity.

conclusions

Indexed as

LichensUsneaAntioxidantsPhenolsTerpenesAntioxidantsPhenolsTerpenesantioxidant activitycytotoxicityphenolic metabolitesUsnea aurantiaco-atrausnic acid

Identifiers

PMID37959736
PMCPMC10649588
OpenAlexW4388010048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.