Evidence map›Paper›PMID 37959702›Full record

ArticleMolecules (Basel, Switzerland)2023

The Synthesis of Novel

Dayana Mesa, Yarelys E Augusto, Giselle Hernández, Juan P Figueroa-Macías, Francisco Coll, Andrés F Olea, María Núñez, Hernán Astudillo Campo, Yamilet Coll, Luis Espinoza

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Dayana MesaCenter for Natural Product Researches, Faculty of Chemistry, University of Havana, Zapata and G, Vedado, Havana 10400, Cuba.
Yarelys E AugustoCenter for Natural Product Researches, Faculty of Chemistry, University of Havana, Zapata and G, Vedado, Havana 10400, Cuba.
Giselle HernándezCenter for Natural Product Researches, Faculty of Chemistry, University of Havana, Zapata and G, Vedado, Havana 10400, Cuba.
Juan P Figueroa-MacíasCenter for Natural Product Researches, Faculty of Chemistry, University of Havana, Zapata and G, Vedado, Havana 10400, Cuba.
Francisco CollCenter for Natural Product Researches, Faculty of Chemistry, University of Havana, Zapata and G, Vedado, Havana 10400, Cuba.
Andrés F OleaGrupo QBAB, Facultad de Ingeniería, Instituto de Ciencias Químicas Aplicadas, Universidad Autónoma de Chile, Llano Subercaseaux 2801, Santiago 7500912, Chile.ORCID 0000-0001-8007-6264
María NúñezDepartamento de Química, Universidad Técnica Federico Santa María, Av. España No. 1680, Valparaíso 2390123, Chile.
Hernán Astudillo CampoGrupo de Investigación en Procesos Electroquímicos, Departamento de Química, Universidad del Cauca, Calle 5 No. 4-70, Popayán 190003, Colombia.
Yamilet CollCenter for Natural Product Researches, Faculty of Chemistry, University of Havana, Zapata and G, Vedado, Havana 10400, Cuba.
Luis EspinozaDepartamento de Química, Universidad Técnica Federico Santa María, Av. España No. 1680, Valparaíso 2390123, Chile.ORCID 0000-0002-4054-7487
University of Havana · CUFederico Santa María Technical University · CLUniversidad Autónoma de Chile · CLUniversity of Cauca · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have demonstrated the antiproliferative and cytotoxic effects of aza-steroids and steroidal sapogenins on human cancer cell lines. The scientific community has shown a growing interest in these compounds as drug candidates for cancer treatment. In the current work, we report the synthesis of new diosgenin oxime derivatives as potential antiproliferative agents. From (25

Indexed as

Antineoplastic AgentsDiosgeninCyanoketoneHumansKetonesOximesSteroidsAntineoplastic AgentsCyanoketoneDiosgeninKetonesOximesSteroidsspirostanic oximessteroidal oximessteroids

Identifiers

PMID37959702
PMCPMC10649921
OpenAlexW4387957865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.