Evidence map›Paper›PMID 37959679›Full record

ArticleMolecules (Basel, Switzerland)2023

In Vitro Antifungal Activity of Selected Essential Oils against Drug-Resistant Clinical

Valeria Allizond, Lorenza Cavallo, Janira Roana, Narcisa Mandras, Anna Maria Cuffini, Vivian Tullio, Giuliana Banche

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Valeria AllizondDepartment Public Health and Pediatrics, Microbiology Division, University of Torino, 10126 Turin, Italy.ORCID 0000-0003-0585-9247
Lorenza CavalloDepartment Public Health and Pediatrics, Microbiology Division, University of Torino, 10126 Turin, Italy.ORCID 0000-0002-8701-8486
Janira RoanaDepartment Public Health and Pediatrics, Microbiology Division, University of Torino, 10126 Turin, Italy.ORCID 0000-0003-2542-622X
Narcisa MandrasDepartment Public Health and Pediatrics, Microbiology Division, University of Torino, 10126 Turin, Italy.ORCID 0000-0002-2949-4556
Anna Maria CuffiniDepartment Public Health and Pediatrics, Microbiology Division, University of Torino, 10126 Turin, Italy.
Vivian TullioDepartment Public Health and Pediatrics, Microbiology Division, University of Torino, 10126 Turin, Italy.ORCID 0000-0002-8660-4248
Giuliana BancheDepartment Public Health and Pediatrics, Microbiology Division, University of Torino, 10126 Turin, Italy.ORCID 0000-0003-2219-0223
University of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTreatment options for aspergillosis include amphotericin B (AMB) and azole compounds, such as itraconazole (ITZ). However, serious side effects related to these antifungal agents are increasingly evident, and resistance continues to increase. Currently, a new trend in drug discovery to overcome this problem is represented by natural products from plants, or their extracts. Particularly, there is a great interest in essential oils (EOs) recognized for their antimicrobial role towards bacteria, fungi and viruses.

methodsIn this study, we evaluated the antifungal activity of eleven commercial EOs-clove, eucalyptus, geranium, hybrid lavender, lavender, lemon, lemongrass, neroli, oregano, tea tree and red red thyme-in comparison with AMB and ITZ against

resultsGas chromatography-mass spectrometry analysis displayed two groups of distinct biosynthetical origin: monoterpenes dominated the chemical composition of the most oils. Only two aromatic compounds (eugenol 78.91% and eugenyl acetate 11.64%) have been identified as major components in clove EO. Lemongrass EO exhibits the strongest antimicrobial activity with a minimum inhibitory concentration of 0.56 mg/mL and a minimum fungicidal concentration of 2.25-4.5 mg/mL against

conclusionsThese results demonstrate the antimicrobial potential of some EOs and support the research of new alternatives or complementary therapies based on EOs.

Indexed as

Antifungal AgentsOils, VolatileAmphotericin BAspergillusFungiItraconazoleMicrobial Sensitivity TestsAmphotericin BAntifungal AgentsItraconazoleOils, Volatileantifungal activityAspergillusclove essential oilessential oilsgeranium essential oillemongrass essential oil

Identifiers

PMID37959679
PMCPMC10650698
OpenAlexW4387937710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.