Evidence map›Paper›PMID 37959657›Full record

ArticleMolecules (Basel, Switzerland)2023

A pH-Sensitive Fluorescent Chemosensor Turn-On Based in a Salen Iron (III) Complex: Synthesis, Photophysical Properties, and Live-Cell Imaging Application.

Nicole Nilo, Mauricio Reyna-Jeldes, Alejandra A Covarrubias, Claudio Coddou, Vania Artigas, Mauricio Fuentealba, Luis F Aguilar, Marianela Saldías, Marco Mellado

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nicole NiloInstituto de Química, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Valparaíso 2373223, Chile.ORCID 0009-0005-9538-7897
Mauricio Reyna-JeldesLaboratory of Cancer Biology, Department of Oncology, Old Road Campus Research Building, University of Oxford, Oxford OX3 7DQ, UK.ORCID 0000-0002-5842-9307
Alejandra A CovarrubiasLaboratorio de Señalización Purinérgica, Departamento de Ciencias Biomédicas, Facultad de Medicina, Universidad Católica del Norte, Coquimbo 1781421, Chile.ORCID 0000-0003-1132-4126
Claudio CoddouLaboratorio de Señalización Purinérgica, Departamento de Ciencias Biomédicas, Facultad de Medicina, Universidad Católica del Norte, Coquimbo 1781421, Chile.ORCID 0000-0002-5297-3694
Vania ArtigasInstituto de Química, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Valparaíso 2373223, Chile.ORCID 0000-0003-1415-8362
Mauricio FuentealbaInstituto de Química, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Valparaíso 2373223, Chile.ORCID 0000-0002-2152-2102
Luis F AguilarInstituto de Química, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Valparaíso 2373223, Chile.ORCID 0000-0002-6038-3475
Marianela SaldíasInstituto de Investigación y Postgrado, Facultad de Ciencias de la Salud, Universidad Central de Chile, Santiago 8330507, Chile.ORCID 0000-0002-5036-0392
Marco MelladoInstituto de Investigación y Postgrado, Facultad de Ciencias de la Salud, Universidad Central de Chile, Santiago 8330507, Chile.ORCID 0000-0001-9577-5180

Funding

Agencia Nacional de Investigación y Desarrollo CONICYT grant 21180850Agencia Nacional de Investigación y Desarrollo Convocatoria Nacional Subvención a Instalación en la Academia Convocatoria año 2021 Folio SA77210078Agencia Nacional de Investigación y Desarrollo Fondecyt Iniciacion grant 11220983Agencia Nacional de Investigación y Desarrollo Fondecyt Postdoctorado grant 3200787Agencia Nacional de Investigación y Desarrollo Fondequip grant EQM120095Agencia Nacional de Investigación y Desarrollo: Becas Chile Scholarship for Doctoral Studies 72220004Ministry of Science, Technology, Knowledge and Innovation Millennium Scientific Initiative NCN19_038Universidad Católica del Norte VRIDT UCN 20210401007
6 · The paper itself

Abstract

pH regulation is essential to allow normal cell function, and their imbalance is associated with different pathologic situations, including cancer. In this study, we present the synthesis of 2-(((2-aminoethyl)imino)methyl)phenol (HL1) and the iron (III) complex (Fe(L1)

Indexed as

Fluorescent DyesIronCell LineEthylenediaminesHumansHydrogen-Ion ConcentrationSpectrometry, Fluorescencedisalicylaldehyde ethylenediamineEthylenediaminesFluorescent DyesIronfluorescence turn-ongastric cancerlactatelive cell imagingmetabolic sensorpH chemosensor

Identifiers

PMID37959657
PMCPMC10647502

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.