Evidence map›Paper›PMID 37959413›Full record

ArticleJournal of clinical medicine2023

Real-World Efficacy and Safety of an 8-Week Glecaprevir/Pibrentasvir Regimen in Children and Adolescents with Chronic Hepatitis C-Results of a Multicenter EpiTer-2 Study.

Malgorzata Pawlowska, Krystyna Dobrowolska, Justyna Moppert, Maria Pokorska-Śpiewak, Mariola Purzynska, Magdalena Marczynska, Dorota Zarebska-Michaluk, Robert Flisiak

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Malgorzata PawlowskaDepartment of Infectious Diseases and Hepatology, Faculty of Medicine, Collegium Medicum Bydgoszcz, Nicolaus Copernicus University, 87-100 Torun, Poland.ORCID 0000-0002-6044-0425
Krystyna DobrowolskaCollegium Medicum, Jan Kochanowski University, 25-317 Kielce, Poland.ORCID 0000-0003-0352-9893
Justyna MoppertDepartment of Infectious Diseases and Hepatology, Faculty of Medicine, Collegium Medicum Bydgoszcz, Nicolaus Copernicus University, 87-100 Torun, Poland.ORCID 0000-0001-6299-2103
Maria Pokorska-ŚpiewakDepartment of Children's Infectious Diseases, Medical University of Warsaw, 01-201 Warsaw, Poland.ORCID 0000-0001-7783-6904
Mariola PurzynskaPomeranian Centre of Department of Infectious Diseases and Observation for Children, Smoluchowskiego 18, 80-214 Gdansk, Poland.
Magdalena MarczynskaDepartment of Children's Infectious Diseases, Medical University of Warsaw, 01-201 Warsaw, Poland.ORCID 0000-0001-5731-6346
Dorota Zarebska-MichalukDepartment of Infectious Diseases and Allergology, Jan Kochanowski University, 25-317 Kielce, Poland.ORCID 0000-0003-0938-1084
Robert FlisiakDepartment of Infectious Diseases and Hepatology, Medical University of Białystok, 15-540 Bialystok, Poland.ORCID 0000-0003-3394-1635
Jan Kochanowski University · PLMedical University of Warsaw · PLNicolaus Copernicus University · PLMedical University of Białystok · PL

Funding

Polish Society of Epidemiologists and Doctors of Infectious Diseases N/A
6 · The paper itself

Abstract

The aim of the study was to analyze the effectiveness and safety of anti-HCV treatment based on a pangenotypic direct-acting antiviral (DAA) regimen with glecaprevir/pibrentasvir (GLE/PIB) in children. The multi-center study was conducted in HCV-infected children who were treated in the period from November 2022 to January 2023. The analysis included 23 pediatric patients with a mean (SD) age of 9.61 (3.68) years. The cohort included 13 girls and 10 boys. The most common HCV genotypes were GT1b (

Indexed as

childrenHCV infectionpangenotypic DAA therapy

Identifiers

PMID37959413
PMCPMC10647729
OpenAlexW4388407617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.