ReviewJournal of clinical medicine2023
Prognosis of Adrenal Oncocytic Neoplasms (AONs): Literature Review of 287 Cases and Presentation of the Oldest Patient.
Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 22 citations in OpenAlex.
- A decade of survival in recurrent nonfunctioning oncocytic adrenocortical carcinoma in a young Filipina.JCEM case reports · 2026Article
- Clinical and pathological features of oncocytic adrenocortical carcinoma: a retrospective comparative study.Journal of endocrinological investigation · 2026Article
- Oncocytoma Arising From an Accessory Adrenal Gland: A Case Report.IJU case reports · 2026Article
- Oncocytic adrenal adenoma: Diagnostic challenge of an incidentaloma; a case report.Urology case reports · 2026Article
- Oncocytic Adrenocortical Carcinoma with Somatic Pathogenic Variants ofDiagnostics (Basel, Switzerland) · 2026Article
- Uncommon tumor, uncertain course: functional oncocytic adrenocortical neoplasm with mild autonomous cortisol secretion.JCEM case reports · 2026Article
- Genomic Sequencing in Oncocytic Adrenal Carcinoma May Provide Insights into Disease Progression and Treatment Options.JCEM case reports · 2025Article
- Non-functional oncocytic adrenocortical carcinoma: Case report with clinicopathologic and surgical correlation.Urology case reports · 2025Article
- Oncocytic Carcinoma: A Rare Hormone-Producing Tumor.Cureus · 2025Article
- Article
- Postoperative feedback-oriented health education in ambulatory robot-assisted adrenalectomy: a single-center nursing intervention cohort study.Journal of robotic surgery · 2025Article
- Adrenal oncocytoma: a rare presentation of a benign 18 F-fluorodeoxyglucose PET avid virilising adrenal tumour.Nuclear medicine communications · 2025Article
- Giant Adrenal Neuroblastoma in Adults: Surgical Management and Comprehensive Review.Clinical case reports · 2025Article
- Atypical clinical presentation of oncocytic adrenocortical carcinoma with decompensated metabolic syndrome and psychotic outbreak.BMJ case reports · 2025Article
- Article
- Oncocytic Adrenal Tumors: A Tri-Focal Review with Integrated Cytopathological, Pathological, and Molecular Perspectives.Acta cytologica · 2025Review
- The value of CT texture analysis in predicting mitotic activity and morphological variants of adrenocortical carcinoma.Frontiers in radiology · 2025Article
- Case report - Adrenal collision tumour composed of oncocytoma and pheochromocytoma.Frontiers in oncology · 2025Article
- Outcomes and Follow-Up Trends in Adrenal Leiomyosarcoma: A Comprehensive Literature Review and Case Report.Journal of clinical medicine · 2024Review
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe adrenocortical oncocytic neoplasms (AONs) are rare tumors of the adrenal gland, classified as oncocytoma (AO), oncocytic neoplasm of uncertain malignant potential (AONUMP) and oncocytic carcinoma (AOC). The aim of this study was to perform a review of the literature, in order to evaluate the prognosis of these rare cancers. We also reported the oldest patient with AON.
methodsA comprehensive literature review using as key words "adrenal oncocytoma", "adrenal oncocytic neoplasm", and "adrenal oncocytic carcinoma" was performed. REPORT OF THE CASE: We report the case of an 88-year-old woman receiving a left open adrenalectomy for an AON (15 × 10 × 8 cm). The considerable size and weight together with the presence of necrosis were indicative for a lesion with an uncertain potential for malignancy, according to Weiss modified criteria. After two years, the patient was free from any sign of recurrence.
resultsOnly 287 AONs were detected in the scientific literature, exploring OVID, MEDLINE, PubMed and SCOPUS as dataset. These tumors are usually incidentalomas with an unpredictable malignant potential. Surgical resection remains the mainstay of treatment for AON.
conclusionAO and AONUMP have an excellent prognosis and a low mortality rate, with only three cases of recurrence reported in the literature and one metastatic case four years after first adrenal surgery. In contrast, AOC carries a high risk of local relapses, distant metastasis, and a significantly higher mortality rate (30%). Surgical resection remains the primary treatment for adrenal oncocytic neoplasms.
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