Evidence map›Paper›PMID 37959371›Full record

ArticleJournal of clinical medicine2023

Monitoring Cochlear Nerve Action Potential for Hearing Preservation in Medium/Large Vestibular Schwannoma Surgery: Tips and Pitfalls.

Baptiste Hochet, Hannah Daoudi, Etienne Lefevre, Yann Nguyen, Isabelle Bernat, Olivier Sterkers, Ghizlene Lahlou, Michel Kalamarides

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Surgery in NF2-Schwannomatosis.Familial cancer · 2025
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Baptiste HochetDépartement d'Oto-Rhino-Laryngologie, Groupe Hospitalo-Universitaire Pitié-Salpêtrière, APHP, Sorbonne Université, 75013 Paris, France.
Hannah DaoudiDépartement d'Oto-Rhino-Laryngologie, Groupe Hospitalo-Universitaire Pitié-Salpêtrière, APHP, Sorbonne Université, 75013 Paris, France.ORCID 0000-0002-7826-0721
Etienne LefevreDépartement de Neurochirurgie, Groupe Hospitalo-Universitaire Pitié-Salpêtrière, APHP, Sorbonne Université, 75013 Paris, France.
Yann NguyenDépartement d'Oto-Rhino-Laryngologie, Groupe Hospitalo-Universitaire Pitié-Salpêtrière, APHP, Sorbonne Université, 75013 Paris, France.
Isabelle BernatDépartement de Neurophysiologie, Groupe Hospitalier Pitié-Salpétrière, APHP, Sorbonne Université, 75013 Paris, France.
Olivier SterkersDépartement d'Oto-Rhino-Laryngologie, Groupe Hospitalo-Universitaire Pitié-Salpêtrière, APHP, Sorbonne Université, 75013 Paris, France.
Ghizlene LahlouDépartement d'Oto-Rhino-Laryngologie, Groupe Hospitalo-Universitaire Pitié-Salpêtrière, APHP, Sorbonne Université, 75013 Paris, France.ORCID 0000-0002-1067-045X
Michel KalamaridesDépartement de Neurochirurgie, Groupe Hospitalo-Universitaire Pitié-Salpêtrière, APHP, Sorbonne Université, 75013 Paris, France.
Institut Pasteur · FRSorbonne Université · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis of large vestibular schwannomas (VS) with retained useful hearing has become increasingly common. Preservation of facial nerve (FN) function has improved using intraoperative EMG monitoring, hearing preservation remains challenging, with the recent use of cochlear nerve action potential (CNAP) monitoring. This prospective longitudinal series of VS with useful hearing operated on using a retrosigmoid approach included 37 patients with a mean largest extrameatal VS. diameter of 25 ± 8.7 mm (81% of Koos stage 4). CNAP was detected in 51% of patients, while auditory brainstem responses (ABR) were present in 22%. Patients were divided into two groups based on the initial intraoperative CNAP status, whether it was present or absent. FN function was preserved (grade I-II) in 95% of cases at 6 months. Serviceable hearing (class A + B) was preserved in 16% of the cases, while 27% retained hearing with intelligibility (class A-C). Hearing with intelligibility (class A-C) was preserved in 42% of cases when CNAP could be monitored in the early stages of VS resection versus 11% when it was initially absent. Changes in both the approach to the cochlear nerve and VS resection are mandatory in preserving CNAP and improve the rate of hearing preservation.

Indexed as

acoustic neuromaCNAPcochlear nervehearingretrosigmoid approach

Identifiers

PMID37959371
PMCPMC10650419
OpenAlexW4388233542

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.