Evidence map›Paper›PMID 37959242›Full record

ArticleJournal of clinical medicine2023

Optimal Lymphadenectomy in Patients with Well-Differentiated Nonfunctioning Pancreatic Neuroendocrine Neoplasms.

Ryuta Shintakuya, Kenichiro Uemura, Tatsuaki Sumiyoshi, Kenjiro Okada, Kenta Baba, Takumi Harada, Yoshiaki Murakami, Masahiro Serikawa, Yasutaka Ishii, Koji Arihiro and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Ryuta ShintakuyaDepartment of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 739-8526, Japan.ORCID 0000-0002-6277-9836
Kenichiro UemuraDepartment of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 739-8526, Japan.ORCID 0000-0003-0003-6268
Tatsuaki SumiyoshiDepartment of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 739-8526, Japan.
Kenjiro OkadaDepartment of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 739-8526, Japan.
Kenta BabaDepartment of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 739-8526, Japan.
Takumi HaradaDepartment of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 739-8526, Japan.
Yoshiaki MurakamiDepartment of Advanced Medicine, Hiroshima University, Hiroshima 739-8526, Japan.
Masahiro SerikawaDepartment of Gastroenterology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 739-8526, Japan.ORCID 0000-0001-8350-7947
Yasutaka IshiiDepartment of Gastroenterology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 739-8526, Japan.ORCID 0000-0003-3545-8743
Koji ArihiroDepartment of Anatomical Pathology, Hiroshima University, Hiroshima 739-8526, Japan.
Shinya TakahashiDepartment of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 739-8526, Japan.
Hiroshima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the optimal extent of lymphadenectomy in patients with nonfunctioning pancreatic neuroendocrine neoplasms. We retrospectively analyzed the clinicopathological data of patients with nonfunctioning pancreatic neuroendocrine neoplasms who underwent surgical resection. We investigated the frequency of metastases at each lymph node station according to tumor location and analyzed the factors contributing to poor overall survival (OS) and disease-free survival (DFS). Overall, data of 84 patients were analyzed. Among patients with pancreatic head tumors, metastases at stations 8, 13, and 17 were found in one (3.1%), four (12.5%), and three (9.3%) patients, respectively. However, none of the other stations showed metastases. For pancreatic body and tail tumors, metastases only at station 11 were found in two (5.1%) patients. Additionally, multivariate DFS and OS analyses showed that lymph node metastasis was the only independent prognostic factor. In conclusion, lymph node metastasis near the primary tumor was the only independent factor of poor prognosis in patients with nonfunctioning pancreatic neuroendocrine neoplasms after undergoing curative surgery. Peri-pancreatic lymphadenectomy might be recommended for nonfunctioning pancreatic neuroendocrine neoplasms.

Indexed as

lymph node dissectionnonfunctioning pancreatic neuroendocrine neoplasmssurgical resection

Identifiers

PMID37959242
PMCPMC10647402
OpenAlexW4388203114

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.