Evidence map›Paper›PMID 37959241›Full record

ArticleJournal of clinical medicine2023

Living Donors' Age Modifies the Impact of Pre-Donation Estimated Glomerular Filtration Rate on Graft Survival.

Manuela Almeida, Catarina Ribeiro, José Silvano, Sofia Pedroso, Sandra Tafulo, La Salete Martins, Miguel Ramos, Jorge Malheiro

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Longitudinal Trajectories of Estimated Glomerular Filtration Rate in a European Population of Living Kidney Donors.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Manuela AlmeidaDepartment of Nephrology, Centro Hospitalar Universitário de Santo António (CHUdSA), 4099-001 Porto, Portugal.ORCID 0000-0002-0312-3685
Catarina RibeiroDepartment of Nephrology, Centro Hospitalar Universitário de Santo António (CHUdSA), 4099-001 Porto, Portugal.
José SilvanoDepartment of Nephrology, Centro Hospitalar Universitário de Santo António (CHUdSA), 4099-001 Porto, Portugal.
Sofia PedrosoDepartment of Nephrology, Centro Hospitalar Universitário de Santo António (CHUdSA), 4099-001 Porto, Portugal.
Sandra TafuloUMIB-Unit for Multidisciplinary Research in Biomedicine, ICBAS-School of Medicine and Biomedical Sciences, University of Porto, 4050-348 Porto, Portugal.
La Salete MartinsDepartment of Nephrology, Centro Hospitalar Universitário de Santo António (CHUdSA), 4099-001 Porto, Portugal.ORCID 0000-0002-6110-2102
Miguel RamosDepartment of Urology, Centro Hospitalar Universitário de Santo António (CHUdSA), 4099-001 Porto, Portugal.
Jorge MalheiroDepartment of Nephrology, Centro Hospitalar Universitário de Santo António (CHUdSA), 4099-001 Porto, Portugal.
Universidade do Porto · PTHospital de Santo António · PT

Funding

Fundação para a Ciência e Tecnologia UIDB/00215/2020, UIDP/00215/2020 and 369 LA/P/0064/2020
6 · The paper itself

Abstract

backgroundThe global scarcity of organs for kidney transplants (KTs) has led to the increased acceptance of living donors (LDs) with minor abnormalities to increase the donor pool.. We sought to evaluate the effects of some of these LDs' clinical characteristics (older age, borderline renal function, hypertension, dyslipidemia, smoking, and obesity) on graft outcomes.

methodsWe studied 352 recipients of LDKTs (1998-2020). Firstly, considering the recipients and KT variables, we identified relevant predictors of overall and censored graft failure (GF). Then, adjusting for these predictors, we explored LD variables as predictors of overall and censored GF in a multivariable Cox model.

resultsThe recipients from LD with higher eGFR (≥90 mL/min/1.73 m

conclusionIn our cohort, lower pre-donation eGFR had an impact on GS only in younger LDs. An age-adjusted eGFR cutoff may be pursued for improved donor admissibility.

Indexed as

ageglomerular filtration rategraft survivalkidney transplantationliving donormedically complex living donors

Identifiers

PMID37959241
PMCPMC10649187
OpenAlexW4387957237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.