Evidence map›Paper›PMID 37959182›Full record

ArticleJournal of clinical medicine2023

Short Versus Long Antibiotic Therapy and Risk of Recurrence of Acute Cholangitis Due to Malignant Biliary Strictures.

Philip G Ferstl, Katharina Bremer, Natalie Filmann, Volkhard A J Kempf, Michael Hogardt, Olivier Ballo, Fabian Finkelmeier, Jonel Trebicka, Stefan Zeuzem, Jörg Bojunga and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 2 countries.

Philip G FerstlGoethe University Frankfurt, University Hospital, Medical Clinic 1, 60590 Frankfurt, Germany.
Katharina BremerGoethe University Frankfurt, University Hospital, Medical Clinic 1, 60590 Frankfurt, Germany.
Natalie FilmannGoethe University Frankfurt, Institute of Biostatistics and Mathematical Modeling, 60590 Frankfurt, Germany.
Volkhard A J KempfGoethe University Frankfurt, University Hospital, Institute for Medical Microbiology and Infection Control, University Center of Competence for Infection Control of the State of Hesse, 60590 Frankfurt, Germany.
Michael HogardtGoethe University Frankfurt, University Hospital, Institute for Medical Microbiology and Infection Control, University Center of Competence for Infection Control of the State of Hesse, 60590 Frankfurt, Germany.
Olivier BalloGoethe University Frankfurt, University Hospital, Medical Clinic 2, 60590 Frankfurt, Germany.
Fabian FinkelmeierGoethe University Frankfurt, University Hospital, Medical Clinic 1, 60590 Frankfurt, Germany.ORCID 0000-0001-8559-9910
Jonel TrebickaGoethe University Frankfurt, University Hospital, Medical Clinic 1, 60590 Frankfurt, Germany.
Stefan ZeuzemGoethe University Frankfurt, University Hospital, Medical Clinic 1, 60590 Frankfurt, Germany.
Jörg BojungaGoethe University Frankfurt, University Hospital, Medical Clinic 1, 60590 Frankfurt, Germany.
Mireen Friedrich-RustGoethe University Frankfurt, University Hospital, Medical Clinic 1, 60590 Frankfurt, Germany.
Dirk WalterGoethe University Frankfurt, University Hospital, Medical Clinic 1, 60590 Frankfurt, Germany.
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignancies can cause severe stenosis of the biliary tract and therefore predispose a patient to bacterial cholangitis. Upon endoscopic drainage, antibiotic therapy (AT) is performed according to individual clinical judgement, as the optimal duration of AT is unclear to date, especially in the case of multidrug-resistant organisms (MDROs). In a case-based retrospective study, patients with malignant biliary strictures and acute cholangitis were included upon endoscopic retrograde cholangiography (ERC). The outcome of cases treated with short AT (≤6 days) was compared to that of long AT (≥7 days). Recurrent cholangitis (RC) before scheduled stent exchange was the primary end point. In total, 124 patients were included, with 183 cases of proven cholangitis in total. The overall median duration of AT was 7 days (range 1-20), with 74 cases (40%) receiving short AT and 109 (60%) receiving long AT. Short AT was not an independent risk factor for RC (HR = 0.66,

Indexed as

antibiotic durationcancer-associated cholangitismetal stentmultidrug resistancerecurring cholangitis

Identifiers

PMID37959182
PMCPMC10648096
OpenAlexW4387909005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.