Evidence map›Paper›PMID 37958985›Full record

ArticleInternational journal of molecular sciences2023

Vasculoprotective Potential of Baicalein in Angiotensin II-Infused Abdominal Aortic Aneurysms through Inhibiting Inflammation and Oxidative Stress.

Erna Sulistyowati, Shang-En Huang, Tsung-Lin Cheng, Yu-Ying Chao, Chia-Yang Li, Ching-Wen Chang, Meng-Xuan Lin, Ming-Chung Lin, Jwu-Lai Yeh

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Erna SulistyowatiFaculty of Medicine, University of Islam Malang, Malang City 65145, Indonesia.ORCID 0000-0003-0805-8154
Shang-En HuangDepartment of Pharmacology, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0003-2324-9178
Tsung-Lin ChengDepartment of Physiology, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0001-7080-8652
Yu-Ying ChaoDepartment of Public Health, College of Health Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0001-5192-122X
Chia-Yang LiGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0001-5689-9850
Ching-Wen ChangDepartment of Pharmacology, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Meng-Xuan LinDepartment of Pharmacology, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Ming-Chung LinDepartment of Anesthesiology, Chi Mei Medical Center, Tainan 710, Taiwan.
Jwu-Lai YehDepartment of Pharmacology, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0001-7101-5865
Kaohsiung Medical University · TWChung Hwa University of Medical Technology · TWNational Sun Yat-sen University · TWUniversitas Islam Malang · ID

Funding

Kemdikbud Ristek Dikti Indonesia 313/S2H/LT/DRPM/2021Ministry of Science and Technology of the People's Republic of China MOST 109-2320-B-037-024-MY3Ministry of Science and Technology of the People's Republic of China NSTC 112-2320-B-037-019-MY3
6 · The paper itself

Abstract

Aortic wall inflammation, abnormal oxidative stress and progressive degradation of extracellular matrix proteins are the main characteristics of abdominal aortic aneurysms (AAAs). The nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 3 (NLRP3) inflammasome dysregulation plays a crucial role in aortic damage and disease progression. The first aim of this study was to examine the effect of baicalein (5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one) on AAA formation in apolipoprotein E-deficient (ApoE

Indexed as

Angiotensin IIAortic Aneurysm, AbdominalAnimalsApolipoproteins EDisease Models, AnimalFlavanonesInflammationMaleMiceMice, Inbred C57BLNLR Family, Pyrin Domain-Containing 3 ProteinOxidative StressRatsAngiotensin IIApolipoproteins EbaicaleinFlavanonesNLR Family, Pyrin Domain-Containing 3 Proteinabdominal aortic aneurysmbaicaleininflammationoxidative stressvasculoprotective

Identifiers

PMID37958985
PMCPMC10647516
OpenAlexW4388423345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.