Evidence map›Paper›PMID 37958922›Full record

ArticleInternational journal of molecular sciences2023

Therapeutic Effect and Safety Evaluation of Naringin on

Guanyu Zhao, Qilin Huang, Xiaohan Jing, Lina Huang, Chen Liu, Xiangyi Pan, Zhaorong Li, Sifan Li, Zhengying Qiu, Ruihua Xin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Dual action of herbal compounds inFrontiers in immunology · 2026
    Review
  3. Article
  4. Etrog Citron (Pharmaceutics · 2025
    Review
  5. Article
  6. Naringin's Alleviation of the Inflammatory Response Caused byInternational journal of molecular sciences · 2024
    Article
  7. Effect of SiHuangQingXinWan onFrontiers in pharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Guanyu ZhaoLanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Lanzhou 730050, China.
Qilin HuangLanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Lanzhou 730050, China.
Xiaohan JingLanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Lanzhou 730050, China.
Lina HuangState Key Laboratory of Applied Organic Chemistry, School of Pharmacy, Lanzhou University, Lanzhou 730013, China.
Chen LiuLanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Lanzhou 730050, China.
Xiangyi PanLanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Lanzhou 730050, China.
Zhaorong LiLanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Lanzhou 730050, China.
Sifan LiLanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Lanzhou 730050, China.
Zhengying QiuLanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Lanzhou 730050, China.
Ruihua XinLanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences (CAAS), Lanzhou 730050, China.ORCID 0000-0002-8680-1217
Gansu University of Traditional Chinese Medicine · CNLanzhou University · CN

Funding

Central government guides local science and technology development fund projects in Gansu province 22ZY1QA012Key Research and Development fund of Gansu Province, China 21YF5FA166, 23YFNA0010, 23YFFA0014Lanzhou Science and Technology Project, China 2021-1-159, 2022-RC-21National Key Research and Development Program of China 2022YFD180110304National Natural Science Foundation of China 32002328Natural Science Foundation of Gansu Province 22JR5RA038
6 · The paper itself

Abstract

Critically ill patients with Corona Virus Disease 2019 (COVID-19) often develop secondary bacterial infections that pose a significant threat to patient life safety, making the development of drugs to prevent bacterial infections in the lungs critical to clinical care. Naringin (NAR) is one of the significant natural flavonoids rich in Pummelo Peel (Hua Ju Hong), with anti-inflammatory, antimicrobial, and antioxidant activities, and is commonly used in treating respiratory tract infectious diseases. In this study, the in vitro and in vivo findings revealed that, after

Indexed as

Klebsiella pneumoniaePneumonia, BacterialAnimalsFlavanonesHumansMiceNF-kappa BSignal TransductionTumor Necrosis Factor-alphaFlavanonesnaringinNF-kappa BTumor Necrosis Factor-alphaanti-inflammatorybacterial pneumoniadrug safetyflavonoidsKlebsiella pneumoniae (Kpn)naringin (NAR)

Identifiers

PMID37958922
PMCPMC10650447
OpenAlexW4388289082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.