Evidence map›Paper›PMID 37958885›Full record

ArticleInternational journal of molecular sciences2023

Antioxidant Iron Oxide Nanoparticles: Their Biocompatibility and Bioactive Properties.

Jaewook Lee, Ji-Heon Lee, Seung-Yeul Lee, Sin A Park, Jae Hoon Kim, Dajeong Hwang, Kyung A Kim, Han Sang Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Chitosan-Entrapped TiOPolymers · 2026
    Article
  2. Eco-friendly synthesis of FeFrontiers in microbiology · 2026
    Article
  3. Article
  4. Article
  5. Special Issue "Recent Advances in Nanoparticles in Molecular Biology".International journal of molecular sciences · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jaewook LeeResearch Institute for Biomolecular Chemistry, Dongguk University, Seoul 04620, Republic of Korea.
Ji-Heon Lee4D Convergence Technology Institute (National Key Technology Institute in University), Korea National University of Transportation, Jungpyeong 27909, Republic of Korea.
Seung-Yeul LeeGenomictree, Inc., 44-6 10-ro Techno, Daejeon 34027, Republic of Korea.
Sin A ParkGenomictree, Inc., 44-6 10-ro Techno, Daejeon 34027, Republic of Korea.
Jae Hoon KimGenomictree, Inc., 44-6 10-ro Techno, Daejeon 34027, Republic of Korea.
Dajeong HwangDepartment of Chemical Engineering and Applied Chemistry, Chungnam National University, Daejeon 34134, Republic of Korea.ORCID 0000-0003-4858-1257
Kyung A KimYonsei Cancer Center, Seoul 30722, Republic of Korea.
Han Sang KimYonsei Cancer Center, Seoul 30722, Republic of Korea.ORCID 0000-0002-6504-9927
Korea National University of Transportation · KRYonsei University · KRChungnam National University · KR

Funding

National Research Foundation of Korea 2022R1I1A1A01060691
6 · The paper itself

Abstract

A lot of nanomaterials have been applied to various nano-biotechnological fields, such as contrast agents, drug or gene delivery systems, cosmetics, and so on. Despite the expanding usage of nanomaterials, concerns persist regarding their potential toxicity. To address this issue, many scientists have tried to develop biocompatible nanomaterials containing phytochemicals as a promising solution. In this study, we synthesized biocompatible nanomaterials by using gallic acid (GA), which is a phytochemical, and coating it onto the surface of iron oxide nanoparticles (IONPs). Importantly, the GA-modified iron oxide nanoparticles (GA-IONPs) were successfully prepared through environmentally friendly methods, avoiding the use of harmful reagents and extreme conditions. The presence of GA on the surface of IONPs improved their stability and bioactive properties. In addition, cell viability assays proved that GA-IONPs possessed excellent biocompatibility in human dermal papilla cells (HDPCs). Additionally, GA-IONPs showed antioxidant activity, which reduced intracellular reactive oxygen species (ROS) levels in an oxidative stress model induced by hydrogen peroxide (H

Indexed as

AntioxidantsNanoparticlesFerric CompoundsHumansHydrogen PeroxideMagnetic Iron Oxide NanoparticlesOxidative StressReactive Oxygen SpeciesAntioxidantsFerric CompoundsHydrogen PeroxideReactive Oxygen Speciesantioxidant effectantioxidant iron oxidebiocompatibilitycell protective effectgallic acidiron oxidenanomaterials

Identifiers

PMID37958885
PMCPMC10649306
OpenAlexW4388221724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.