Evidence map›Paper›PMID 37958826›Full record

ArticleInternational journal of molecular sciences2023

Molecular Mechanism Biomarkers Predict Diagnosis in Schizophrenia and Schizoaffective Psychosis, with Implications for Treatment.

Stephanie Fryar-Williams, Graeme Tucker, Jörg Strobel, Yichao Huang, Peter Clements

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Stephanie Fryar-WilliamsYouth in Mind Research Institute, Unley, SA 5061, Australia.ORCID 0000-0001-5397-5459
Graeme TuckerDepartment of Public Health, Faculty of Health and Medical Sciences, Adelaide Medical School, The University of Adelaide, Adelaide, SA 5000, Australia.
Jörg StrobelDepartment of Psychiatry, Faculty of Health and Medical Sciences, Adelaide Medical School, The University of Adelaide, Adelaide, SA 5000, Australia.
Yichao HuangWaite Research Institute, The University of Adelaide, Urrbrae, SA 5064, Australia.
Peter ClementsWaite Research Institute, The University of Adelaide, Urrbrae, SA 5064, Australia.ORCID 0000-0003-1670-2579
The University of Adelaide · AUBasil Hetzel Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnostic uncertainty and relapse rates in schizophrenia and schizoaffective disorder are relatively high, indicating the potential involvement of other pathological mechanisms that could serve as diagnostic indicators to be targeted for adjunctive treatment. This study aimed to seek objective evidence of methylenetetrahydrofolate reductase

Indexed as

Psychotic DisordersSchizophreniaBiomarkersCatecholaminesFolic AcidGenotypeHumansMethylenetetrahydrofolate Reductase (NADPH2)RiboflavinVitaminsBiomarkersCatecholaminesFolic AcidMethylenetetrahydrofolate Reductase (NADPH2)RiboflavinVitaminsbiomarkersbipolarmethylationMTHFR C677T genotypephenotypespsychosisriboflavinschizophreniatreatment applicationsvitamin B6

Identifiers

PMID37958826
PMCPMC10650772
OpenAlexW4388048746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.