Evidence map›Paper›PMID 37958800›Full record

Observational studyInternational journal of molecular sciences2023

Dendritic Cell Subpopulations Are Associated with Prognostic Characteristics of Breast Cancer after Neoadjuvant Chemotherapy-An Observational Study.

Agnieszka Łazarczyk, Joanna Streb, Anna Glajcar, Anna Streb-Smoleń, Przemysław Hałubiec, Kacper Wcisło, Łukasz Laskowicz, Diana Hodorowicz-Zaniewska, Joanna Szpor

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Special Issue "Dendritic Cell and Cancer Therapy 2.0".International journal of molecular sciences · 2025
    Article
  4. ExosomalIranian journal of public health · 2025
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Agnieszka ŁazarczykDepartment of Pathomorphology, Jagiellonian University Medical College, 31-501 Cracow, Poland.ORCID 0000-0002-3336-3321
Joanna StrebDepartment of Oncology, Jagiellonian University Medical College, 31-501 Cracow, Poland.
Anna GlajcarDepartment of Pathomorphology, University Hospital, 30-688 Cracow, Poland.
Anna Streb-SmoleńDepartment of Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, 31-115 Cracow, Poland.
Przemysław HałubiecDoctoral School of Medical and Health Sciences, Jagiellonian University Medical College, 31-530 Cracow, Poland.ORCID 0000-0002-7759-6039
Kacper WcisłoDepartment of Pathomorphology, Jagiellonian University Medical College, 31-501 Cracow, Poland.
Łukasz LaskowiczClinical Department of Gynecology and Gynecological Oncology, University Hospital, 30-688 Cracow, Poland.
Diana Hodorowicz-ZaniewskaGeneral, Oncological and Gastrointestinal Surgery, Jagiellonian University Medical College, 31-501 Cracow, Poland.
Joanna SzporDepartment of Pathomorphology, Jagiellonian University Medical College, 31-501 Cracow, Poland.ORCID 0000-0002-1267-6257
Jagiellonian University · PLCracow University of Technology · PLThe Maria Sklodowska-Curie National Research Institute of Oncology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BC) is the most prevalent malignancy in women and researchers have strived to develop optimal strategies for its diagnosis and management. Neoadjuvant chemotherapy (NAC), which reduces tumor size, risk of metastasis and patient mortality, often also allows for a de-escalation of breast and axillary surgery. Nonetheless, complete pathological response (pCR) is achieved in no more than 40% of patients who underwent NAC. Dendritic cells (DCs) are professional antigen-presenting cells present in the tumor microenvironment. The multitude of their subtypes was shown to be associated with the pathological and clinical characteristics of BC, but it was not evaluated in BC tissue after NAC. We found that highe r densities of CD123

Indexed as

Breast NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsDendritic CellsErb-b2 Receptor Tyrosine KinasesFemaleHumansInterleukin-3 Receptor alpha SubunitNeoadjuvant TherapyPrognosisTumor MicroenvironmentErb-b2 Receptor Tyrosine KinasesInterleukin-3 Receptor alpha Subunitbreast cancerCD123CD1aDC-LAMPDC-SIGNdendritic cellsneoadjuvant chemotherapy

Identifiers

PMID37958800
PMCPMC10648319
OpenAlexW4388082840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.