Evidence map›Paper›PMID 37958782›Full record

ArticleInternational journal of molecular sciences2023

Physiologic and Transcriptomic Effects Triggered by Overexpression of Wild Type and Mutant DNA Topoisomerase I in

Miriam García-López, Pablo Hernández, Diego Megias, María-José Ferrándiz, Adela G de la Campa

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Miriam García-LópezUnidad de Genética Bacteriana, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, 28220 Madrid, Spain.ORCID 0000-0001-6505-3582
Pablo HernándezCentro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain.
Diego MegiasUnidad de Microscopía Confocal, Instituto de Salud Carlos III, Majadahonda, 28220 Madrid, Spain.
María-José FerrándizUnidad de Genética Bacteriana, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, 28220 Madrid, Spain.ORCID 0000-0003-1428-9506
Adela G de la CampaUnidad de Genética Bacteriana, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, 28220 Madrid, Spain.ORCID 0000-0002-3598-2548
Instituto de Salud Carlos III · ESConsejo Superior de Investigaciones Científicas · ES

Funding

MCIN/AEI/10.13039/501100011033/FEDER, UE PID2021-124738OB-100
6 · The paper itself

Abstract

Topoisomerase I (TopoI) in

Indexed as

DNA Topoisomerases, Type ITranscriptomeAnti-Bacterial AgentsDNA GyraseStreptococcus pneumoniaeAnti-Bacterial AgentsDNA GyraseDNA Topoisomerases, Type IDNA supercoilingDNA topoisomerase Iregulation of supercoilingseconeolitsinetranscriptional domains

Identifiers

PMID37958782
PMCPMC10648598
OpenAlexW4388042175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.