Evidence map›Paper›PMID 37958691›Full record

ArticleInternational journal of molecular sciences2023

In Vivo Serotonin 5-HT2A Receptor Availability and Its Relationship with Aggression Traits in Healthy Individuals: A Positron Emission Tomography Study with C-11 MDL100907.

Jeong-Hee Kim, Hang-Keun Kim, Young-Don Son, Jong-Hoon Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Targeting Serotonin 5-HTAggression and violent behavior
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jeong-Hee KimNeuroscience Research Institute, Gachon University, Incheon 21565, Republic of Korea.ORCID 0000-0002-9053-3091
Hang-Keun KimNeuroscience Research Institute, Gachon University, Incheon 21565, Republic of Korea.ORCID 0000-0003-4428-3279
Young-Don SonNeuroscience Research Institute, Gachon University, Incheon 21565, Republic of Korea.ORCID 0000-0001-7029-2422
Jong-Hoon KimNeuroscience Research Institute, Gachon University, Incheon 21565, Republic of Korea.ORCID 0000-0003-3785-1207
Gachon University · KR

Funding

National Research Foundation (NRF) of Korea grant funded by the Korea government (MSIT) NRF-2022R1A2C2009580 and NRF-2020R1A4A1019623
6 · The paper itself

Abstract

Serotonergic neurotransmission has been associated with aggression in several psychiatric disorders. Human aggression is a continuum of traits, ranging from normal to pathological phenomena. However, the individual differences in serotonergic neurotransmission and their relationships with aggression traits in healthy individuals remain unclear. In this study, we explored the relationship between 5-HT2A receptor availability in vivo and aggression traits in healthy participants. Thirty-three healthy participants underwent 3-Tesla magnetic resonance imaging and positron emission tomography (PET) with [

Indexed as

Receptor, Serotonin, 5-HT2ASerotoninAggressionBrainCarbon RadioisotopesHumansMagnetic Resonance ImagingPositron-Emission TomographyCarbon-11Carbon RadioisotopesHTR2A protein, humanReceptor, Serotonin, 5-HT2ASerotonin5-HT2A receptoraggressionC-11 MDL100907positron emission tomographyserotonin

Identifiers

PMID37958691
PMCPMC10647245
OpenAlexW4388021294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.