Evidence map›Paper›PMID 37958668›Full record

ArticleInternational journal of molecular sciences2023

Comparison and Validation of Rapid Molecular Testing Methods for Theranostic Epidermal Growth Factor Receptor Alterations in Lung Cancer: Idylla versus Digital Droplet PCR.

Camille Léonce, Clémence Guerriau, Lara Chalabreysse, Michaël Duruisseaux, Sébastien Couraud, Marie Brevet, Pierre-Paul Bringuier, Delphine Aude Poncet

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Camille LéonceDepartment of Pathology, Tumor Molecular Biology Unit, Groupement Hospitalier Est, Hospices Civils de Lyon, 69394 Bron, France.ORCID 0000-0002-7171-0427
Clémence GuerriauDepartment of Pathology, Tumor Molecular Biology Unit, Groupement Hospitalier Est, Hospices Civils de Lyon, 69394 Bron, France.
Lara ChalabreysseDepartment of Pathology, Tumor Molecular Biology Unit, Groupement Hospitalier Est, Hospices Civils de Lyon, 69394 Bron, France.
Michaël DuruisseauxUniversity of Lyon, Université Claude Bernard Lyon 1, 69100 Lyon, France.
Sébastien CouraudUniversity of Lyon, Université Claude Bernard Lyon 1, 69100 Lyon, France.
Marie BrevetDepartment of Pathology, Tumor Molecular Biology Unit, Groupement Hospitalier Est, Hospices Civils de Lyon, 69394 Bron, France.
Pierre-Paul BringuierDepartment of Pathology, Tumor Molecular Biology Unit, Groupement Hospitalier Est, Hospices Civils de Lyon, 69394 Bron, France.
Delphine Aude PoncetDepartment of Pathology, Tumor Molecular Biology Unit, Groupement Hospitalier Est, Hospices Civils de Lyon, 69394 Bron, France.ORCID 0000-0003-0446-5262
Université Claude Bernard Lyon 1 · FRCentre National de la Recherche Scientifique · FR

Funding

AstraZeneca (France) 2019-019353-ECBiocartis (Switzerland) provision of deviceFondation ARC pour la Recherche sur le Cancer 2022ARCPGA2021120004256_4864Fondation ARC pour la Recherche sur le Cancer PJA 20151203400Hospices Civils de Lyon Young Researcher programInserm contrat interface inserm pour hospitalier
6 · The paper itself

Abstract

Targeting EGFR alterations, particularly the L858R (Exon 21) mutation and Exon 19 deletion (del19), has significantly improved the survival of lung cancer patients. From now on, the issue is to shorten the time to treatment. Here, we challenge two well-known rapid strategies for

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsErbB ReceptorsHumansMolecular Diagnostic TechniquesMutationPolymerase Chain ReactionPrecision MedicineErbB ReceptorsddPCRdiagnosisepidermal growth factor receptorIdyllaLUADlung cancermethod validationNSCLC

Identifiers

PMID37958668
PMCPMC10648419
OpenAlexW4387971167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.