Evidence map›Paper›PMID 37958642›Full record

ArticleInternational journal of molecular sciences2023

Combined Inhibition of

Keying Liang, Qian Wang, Li Qiu, Xiaocheng Gong, Zixi Chen, Haibo Zhang, Ke Ding, Yunfei Liu, Jinfen Wei, Shudai Lin and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Special Issue: "Drug Repurposing for Cancer Therapies".International journal of molecular sciences · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Keying LiangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.ORCID 0009-0008-9238-4959
Qian WangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Li QiuSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Xiaocheng GongSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Zixi ChenSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Haibo ZhangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Ke DingSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Yunfei LiuSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Jinfen WeiSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Shudai LinSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.ORCID 0000-0002-8520-8614
Shuying FuSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Hongli DuSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
South China University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Various studies have shown that the cell-cycle-related regulatory proteins UBE2C, PLK1, and BIRC5 promote cell proliferation and migration in different types of cancer. However, there is a lack of in-depth and systematic research on the mechanism of these three as therapeutic targets. In this study, we found a positive correlation between the expression of

Indexed as

NeoplasmsCell Cycle ProteinsCell DivisionCell Line, TumorCell ProliferationHumansUbiquitin-Conjugating EnzymesCell Cycle ProteinsUBE2C protein, humanUbiquitin-Conjugating EnzymesATP-citrate lyase (ACLY)baculoviral IAP repeat containing 5 (BIRC5)cell cyclecell proliferationde novo lipogenesis (DNL)pan-cancerpolo-like kinase 1 (PLK1)ubiquitin conjugating enzyme E2 C (UBE2C)

Identifiers

PMID37958642
PMCPMC10650476
OpenAlexW4388192325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.