Effects of Superficial Scratching and Engineered Nanomaterials on Skin Gene Profiles and Microbiota in SKH-1 Mice.

Kuunsäde Mäenpää, Marit Ilves, Lan Zhao, Harri Alenius, Hanna Sinkko, Piia Karisola

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.1field-weighted citation impact, top 47% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

Green Synthesis of Zinc Oxide Nanoparticles fromInternational journal of nanomedicine · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Kuunsäde MäenpääHuman Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0002-5531-1186

Marit IlvesHuman Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.

Lan ZhaoHuman Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.ORCID 0009-0000-3696-4280

Harri AleniusHuman Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0003-0106-8923

Hanna SinkkoHuman Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.

Piia KarisolaHuman Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0003-0635-2704

University of Helsinki · FI

Funding

Academy of Finland 1333178Academy of Finland 307768Finnish Cultural Foundation Personal funding

6 · The paper itself

Abstract

Scratching damages upper layers of the skin, breaks this first line of immune defence, and leads to inflammation response, which often also modifies the microbiota of the skin. Although the healing of incision wounds is well-described, there are fewer studies on superficial wounds. We used a simulated model of skin scratching to study changes in the host transcriptome, skin microbiota, and their relationship. Additionally, we examined the effect of nanosized ZnO, TiO

Indexed as

MicrobiotaSkinAdministration, CutaneousAnimalsMiceNeutrophilsWound Healingchemotaxisinflammationmetal oxidesmicrobiotamouse modelnanoparticlesRSEQscratchingwound

Identifiers

PMID37958613

DOI10.3390/ijms242115629

PMCPMC10649582

OpenAlexW4387971927

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.