Evidence map›Paper›PMID 37958589›Full record

ArticleInternational journal of molecular sciences2023

Novel Antimicrobial Peptide from the Hepatopancreas of the Red King Crab.

Vladislav Molchanov, Alexander Yegorov, Maxim Molchanov, Alexander Timchenko, Vitaly Novikov, Nikolay Novojilov, Maria Timchenko

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Vladislav MolchanovInstitute of Theoretical and Experimental Biophysics RAS, Pushchino 142290, Russia.ORCID 0009-0009-2404-9419
Alexander YegorovInstitute of Theoretical and Experimental Biophysics RAS, Pushchino 142290, Russia.
Maxim MolchanovInstitute of Theoretical and Experimental Biophysics RAS, Pushchino 142290, Russia.
Alexander TimchenkoInstitute of Protein Research RAS, Pushchino 142290, Russia.
Vitaly NovikovPolar Branch of Russian Federal Research Institute of Fisheries and Oceanography, Murmansk 183038, Russia.ORCID 0000-0003-1733-5838
Nikolay NovojilovM. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.
Maria TimchenkoInstitute of Theoretical and Experimental Biophysics RAS, Pushchino 142290, Russia.ORCID 0000-0003-2547-8804
Institute of Theoretical and Experimental Biophysics · RUInstitute of Bioorganic Chemistry · RUInstitute of Protein Research · RUKnipovich Polar Research Institute of Marine Fisheries and Oceanography · RU

Funding

RSF 23-24-00278
6 · The paper itself

Abstract

Crustaceans have successfully adapted to survive in their natural habitat, rich in microorganisms, due to the presence of antimicrobial peptides (AMPs) in their organism. They achieve this adaptation despite lacking the highly specific adaptive immune system found in vertebrates. One valuable source of AMPs is the hepatopancreas, a waste product from crab fishery and its processing. Applying zymographic and spectrophotometric techniques, we discovered a small peptide (approximately 5 kDa) within a low molecular weight protein fraction extracted from the acetone powder of the red king crab hepatopancreas. This peptide hydrolyzes both

Indexed as

AnomuraBrachyuraAnimalsAntimicrobial PeptidesHepatopancreasAntimicrobial Peptidesantimicrobial peptideshepatopancreasred king crab

Identifiers

PMID37958589
PMCPMC10649287
OpenAlexW4388201030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.