Evidence map›Paper›PMID 37958360›Full record

ArticleCancers2023

Colorectal Pulmonary Metastases: Pulmonary Metastasectomy or Stereotactic Radiotherapy?

Martijn van Dorp, Constantia Trimbos, Wilhelmina H Schreurs, Chris Dickhoff, David J Heineman, Bart Torensma, Geert Kazemier, Frank J C van den Broek, Ben J Slotman, Max Dahele

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Martijn van DorpAmsterdam University Medical Center, Location VUmc, Department of Cardiothoracic Surgery, 1007 MB Amsterdam, The Netherlands.ORCID 0000-0003-3760-3027
Constantia TrimbosAmsterdam University Medical Center, Location VUmc, Department of Cardiothoracic Surgery, 1007 MB Amsterdam, The Netherlands.
Wilhelmina H SchreursNorthwest Clinics, Department of Surgery, 1815 JD Alkmaar, The Netherlands.
Chris DickhoffAmsterdam University Medical Center, Location VUmc, Department of Cardiothoracic Surgery, 1007 MB Amsterdam, The Netherlands.
David J HeinemanAmsterdam University Medical Center, Location VUmc, Department of Cardiothoracic Surgery, 1007 MB Amsterdam, The Netherlands.ORCID 0009-0002-0720-7015
Bart TorensmaDepartment of Anesthesiology, Leiden University Medical Centre, 2333 ZA Leiden, The Netherlands.ORCID 0000-0003-0274-9608
Geert KazemierCancer Center Amsterdam, Imaging and Biomarkers, 1081 HV Amsterdam, The Netherlands.
Frank J C van den BroekMáxima Medical Centra, Department of Surgery, 5657 EG Veldhoven, The Netherlands.ORCID 0000-0002-4828-5725
Ben J SlotmanCancer Center Amsterdam, Imaging and Biomarkers, 1081 HV Amsterdam, The Netherlands.
Max DaheleCancer Center Amsterdam, Imaging and Biomarkers, 1081 HV Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLLeiden University · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary metastasectomy and stereotactic ablative radiotherapy (SABR) are both guideline-recommended treatments for selected patients with oligometastatic colorectal pulmonary metastases. However, there is limited evidence comparing these local treatment modalities in similar patient groups.

methodsWe retrospectively reviewed records of consecutive patients treated for colorectal pulmonary metastases with surgical metastasectomy or SABR from 2012 to 2019 at two Dutch referral hospitals that had different approaches toward the local treatment of colorectal pulmonary metastases, one preferring surgery, the other preferring SABR. Two comparable patient groups were identified based on tumor and treatment characteristics.

resultsThe metastasectomy group comprised 40 patients treated for 69 metastases, and the SABR group had 60 patients who were treated for 90 metastases. Median follow-up was 38 months (IQR: 26-67) in the surgery group and 46 months (IQR: 30-79) in the SABR group. Median OS was 58 months (CI: 20-94) in the metastasectomy group and 70 months (CI: 29-111) in the SABR group (

conclusionIn this retrospective cohort study, pulmonary metastasectomy and SABR had comparable overall survival, local recurrence-free survival, and complication rates, despite patients in the SABR group having a significantly lower progression-free survival and local control rate. These data would support a randomized controlled trial comparing surgery and SABR in operable patients with radically resectable colorectal pulmonary metastases.

Indexed as

colorectal lung metastasesoligometastatic colorectal cancerpulmonary metastasectomyRCTSABR

Identifiers

PMID37958360
PMCPMC10647532
OpenAlexW4388009510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.