Evidence map›Paper›PMID 37958295›Full record

ArticleCancers2023

Symptom Clusters in Survivorship and Their Impact on Ability to Work among Cancer Survivors.

Joanna E Fardell, Sim Yee Cindy Tan, Kim Kerin-Ayres, Haryana M Dhillon, Janette L Vardy

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Factors associated with health-related quality of life in survivors of childhood-onset and adult-onset cancer compared to controls.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Multidomain predictors of long-term work disability in late survivorship after head and neck cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joanna E FardellUNSW Medicine & Health, School of Clinical Medicine, UNSW Sydney, Sydney 1466, Australia.
Sim Yee Cindy TanSydney Medical School, Faculty of Medicine and Health, University of Sydney, Sydney 2006, Australia.
Kim Kerin-AyresConcord Cancer Centre, Concord Repatriation General Hospital, Sydney 2139, Australia.ORCID 0009-0004-5647-4202
Haryana M DhillonPsycho-Oncology Cooperative Research Group, School of Psychology, Faculty of Science, University of Sydney, Sydney 2006, Australia.
Janette L VardySydney Medical School, Faculty of Medicine and Health, University of Sydney, Sydney 2006, Australia.ORCID 0000-0002-5739-5790

Funding

National Health and Medical Research Council APP1176221
6 · The paper itself

Abstract

backgroundCancer survivors often experience a range of symptoms after treatment which can impact their quality of life. Symptoms may cluster or co-occur. We aimed to investigate how symptoms and symptom clusters impact the ability to work among cancer survivors.

methodsWe used symptom severity data and ability to work data routinely collected from cancer survivors attending a survivorship clinic after primary treatment with curative intent. We defined symptom clusters using single linkage and a threshold on the rescaled distances of <10. We then conducted a logistic regression to examine how symptoms and symptom clusters were related to the ability to work.

resultsWe analysed data from 561 cancer survivors, mean age 58 years and 1.5 years post diagnosis, with mixed diagnoses including breast (40.5%), colorectal (32.3%), and haematological cancers (15.3%). Limitations to work ability were reported by 34.9% of participants. Survivors experiencing pain, emotional, and cognitive symptom clusters were 14-17% more likely to report limitations in their ability to work. Older survivors and those with a higher stage disease were more likely to report limitations in their ability to work.

conclusionA better understanding and management of symptom severity and symptom clusters may help the sizable proportion of cancer survivors experiencing symptoms to participate in work after treatment.

Indexed as

anxietycancercognitive symptomsdepressionfatiguepainsurvivorsymptomswork

Identifiers

PMID37958295
PMCPMC10647426

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.