Evidence map›Paper›PMID 37958224›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Quantitative CT at Follow-Up of COVID-19 Pneumonia: Relationship with Pulmonary Function Tests.

Davide Colombi, Marcello Petrini, Camilla Risoli, Angelo Mangia, Gianluca Milanese, Mario Silva, Cosimo Franco, Nicola Sverzellati, Emanuele Michieletti

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Davide ColombiRadiology Unit, Department of Radiological Functions, AUSL Piacenza, Via Taverna 49, 29121 Piacenza, Italy.ORCID 0000-0002-2794-5237
Marcello PetriniRadiology Unit, Department of Radiological Functions, AUSL Piacenza, Via Taverna 49, 29121 Piacenza, Italy.
Camilla RisoliRadiology Unit, Department of Radiological Functions, AUSL Piacenza, Via Taverna 49, 29121 Piacenza, Italy.ORCID 0000-0003-0117-7011
Angelo MangiaPulmonology Unit, Department of Emergency, AUSL Piacenza, Via Taverna 49, 29121 Piacenza, Italy.
Gianluca MilaneseScienze Radiologiche, Department of Medicine and Surgery (DiMeC), University of Parma, Via Gramsci 14, 43126 Parma, Italy.
Mario SilvaScienze Radiologiche, Department of Medicine and Surgery (DiMeC), University of Parma, Via Gramsci 14, 43126 Parma, Italy.
Cosimo FrancoPulmonology Unit, Department of Emergency, AUSL Piacenza, Via Taverna 49, 29121 Piacenza, Italy.
Nicola SverzellatiScienze Radiologiche, Department of Medicine and Surgery (DiMeC), University of Parma, Via Gramsci 14, 43126 Parma, Italy.
Emanuele MichielettiRadiology Unit, Department of Radiological Functions, AUSL Piacenza, Via Taverna 49, 29121 Piacenza, Italy.
Azienda Unità Sanitaria Locale Piacenza · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe role of quantitative chest computed tomography (CT) is controversial in the follow-up of patients with COVID-19 pneumonia. The aim of this study was to test during the follow-up of COVID-19 pneumonia the association between pulmonary function tests (PFTs) and quantitative parameters extrapolated from follow-up (FU) CT scans performed at least 6 months after COVID-19 onset.

methodsThe study included patients older than 18 years old, admitted to the emergency department of our institution between 29 February 2020 and 31 December 2020, with a diagnosis of COVID-19 pneumonia, who underwent chest CT at admission and FU CT at least 6 months later; PFTs were performed within 6 months of FU CT. At FU CT, quantitative parameters of well-aerated lung and pneumonia extent were identified both visually and by software using CT density thresholds. The association between PFTs and quantitative parameters was tested by the calculation of the Spearman's coefficient of rank correlation (rho).

resultsThe study included 40 patients (38% females; median age 63 years old, IQR, 56-71 years old). A significant correlation was identified between low attenuation areas% (%LAAs) <950 Hounsfield units (HU) and both forced expiratory volume in 1s/forced vital capacity (FEV1/FVC) ratio (rho -0.410, 95% CIs -0.639--0.112,

conclusionsAt follow-up, CT scans performed at least 6 months after COVID-19 pneumonia onset showed %LAAs that were inversely associated with %DLCO and could be considered a marker of irreversible lung damage.

Indexed as

COVID-19post-acute COVID-19 syndromepulmonary emphysema

Identifiers

PMID37958224
PMCPMC10648873
OpenAlexW4387976228

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.