Evidence map›Paper›PMID 37957548›Full record

ArticleBMC microbiology2023

Impact of clonal lineages on susceptibility of Staphylococcus lugdunensis to chlorhexidine digluconate and chloride benzalkonium.

Laurie Destruel, Marine Lecomte, Maxime Grand, Marie Leoz, Martine Pestel-Caron, Sandrine Dahyot

Open access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Laurie DestruelUniv Rouen Normandie, UNICAEN, Inserm, Normandie Univ, DYNAMICURE UMR 1311, F - 76000, Rouen, France.
Marine LecomteUniv Rouen Normandie, UNICAEN, Inserm, Normandie Univ, DYNAMICURE UMR 1311, F - 76000, Rouen, France.
Maxime GrandUniv Rouen Normandie, UNICAEN, Inserm, Normandie Univ, DYNAMICURE UMR 1311, F - 76000, Rouen, France.
Marie LeozUniv Rouen Normandie, UNICAEN, Inserm, Normandie Univ, DYNAMICURE UMR 1311, F - 76000, Rouen, France.
Martine Pestel-CaronUniv Rouen Normandie, UNICAEN, Inserm, Normandie Univ, DYNAMICURE UMR 1311, CHU Rouen, Department of Bacteriology, F - 76000, Rouen, France.
Sandrine DahyotUniv Rouen Normandie, UNICAEN, Inserm, Normandie Univ, DYNAMICURE UMR 1311, CHU Rouen, Department of Bacteriology, F - 76000, Rouen, France. sandrine.dahyot@chu-rouen.fr.
Inserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle is known about susceptibility of Staphylococcus lugdunensis to antiseptics. The objective of this study was to evaluate, at the molecular and phenotypic level, the susceptibility of 49 clinical S. lugdunensis strains (belonging to the seven clonal complexes [CCs] defined by multilocus sequence typing) to two antiseptics frequently used in healthcare settings (chlorhexidine digluconate [CHX] and chloride benzalkonium [BAC]).

resultsThe minimum inhibitory concentrations (MICs), by broth microdilution method, varied for BAC from 0.25 mg/L to 8 mg/L (MIC

conclusionThe norA gene was detected in all the strains, suggesting that it could belong to the core genome of S. lugdunensis. S. lugdunensis is highly susceptible to both antiseptics tested. Reduced susceptibility to BAC and CHX was a rare phenomenon. Of note, a tendency to higher MICs of BAC was detected for CC3 isolates. These results should be confirmed on a larger collection of strains.

Indexed as

Anti-Infective Agents, LocalDisinfectantsStaphylococcus lugdunensisBacterial ProteinsBenzalkonium CompoundsChlorhexidineChloridesMicrobial Sensitivity TestsAnti-Infective Agents, LocalBacterial ProteinsBenzalkonium CompoundsChlorhexidinechlorhexidine gluconateChloridesDisinfectantsAntisepticsBenzalkonium chlorideChlorhexidine digluconateMIC/MBC valuesnorAqacResistanceStaphylococcus lugdunensis

Identifiers

PMID37957548
PMCPMC10642039
OpenAlexW4388633451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.