ArticleVirchows Archiv : an international journal of pathology2024
Solitary fibrous tumours involving the genitourinary tract: a case series in rare locations, highlighting the role of STAT6 immunohistochemistry.
Article in Virchows Archiv : an international journal of pathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 7 citations in OpenAlex.
- [Solitary fibrous tumor of the prostate mimicking a tumor of the vesicoprostatic junction. Case report].Revista medica del Instituto Mexicano del Seguro Social · 2026Article
- Robot-assisted laparoscopic prostate-sparing resection of an extremely rare periprostatic solitary fibrous tumor: a case report and literature review.World journal of surgical oncology · 2025Review
- Solitary fibrous tumor of the prostate with accompanying low-grade prostate cancer.Urology case reports · 2024Article
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8 authors at 4 institutions in 3 countries.
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Abstract
Solitary fibrous tumour (SFT) is a mesenchymal neoplasm with variable behaviour, very rarely involving the genitourinary (GU) tract. Most reported cases correspond to isolated case reports. STAT6 immunohistochemistry is a more recent and reliable diagnostic marker. The pathology database of two tertiary institutes was searched for SFTs involving the GU tract. STAT6 strong diffuse nuclear staining confirmed the diagnosis in all four cases, and the NAB2::STAT6 fusion was demonstrated by NGS in one case. Two cases were diagnosed in needle biopsy, one involving the prostate and the other involving the seminal vesicle. One case corresponded to a pelvic mass inseparable from and infiltrating the prostate and bladder. The remainder represented an exceedingly rare involvement of the spermatic cord. Involvement by a SFT should be considered in the differential diagnosis of spindle cell lesions involving GU organs. STAT6 strong diffuse nuclear staining is an important ancillary tool, particularly in a biopsy.
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