Evidence map›Paper›PMID 37957270›Full record

ArticleNature materials2024

Atomically precise photothermal nanomachines.

Jing Chen, Peilin Gu, Guangliu Ran, Yu Zhang, Mingqiang Li, Bin Chen, Hui Lu, Ying-Zi Han, Wenkai Zhang, Zichao Tang and 13 more

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Nature materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
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  5. Article
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  8. Article
  9. Review
  10. Article
  11. Article
  12. Superhydrophilic FeAngewandte Chemie (International ed. in English) · 2025
    Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Imaging-Guided Microscale Photothermal Stereolithography Bioprinting.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors.

Jing Chen *Institute of Materiobiology, Department of Chemistry, College of Science, Shanghai University, Shanghai, China.
Peilin Gu *Division of Physical Biology, CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, China.
Guangliu Ran *Department of Physics and Applied Optics Beijing Area Major Laboratory, Center for Advanced Quantum Studies, Beijing Normal University, Beijing, China.
Yu Zhang *The Interdisciplinary Research Center, Shanghai Synchrotron Radiation Facility, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, China.ORCID 0000-0001-9856-838X
Mingqiang LiSchool of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, China.ORCID 0000-0001-9854-2251
Bin ChenSchool of Material Science and Chemical Engineering, Ningbo University, Ningbo, China.
Hui LuZhangjiang Laboratory, Shanghai, China.
Ying-Zi HanState Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China.
Wenkai ZhangDepartment of Physics and Applied Optics Beijing Area Major Laboratory, Center for Advanced Quantum Studies, Beijing Normal University, Beijing, China.ORCID 0000-0002-9574-6272
Zichao TangState Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China.
Qinglong YanXiangfu Laboratory, Jiashan, China.
Rui SunThe Interdisciplinary Research Center, Shanghai Synchrotron Radiation Facility, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, China.
Xiaobin FuDivision of Physical Biology, CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, China.
Guorui ChenKey Laboratory of Artificial Structures and Quantum Control (Ministry of Education), Shenyang National Laboratory for Materials Science, School of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, China.ORCID 0000-0002-4919-4796
Zhiwen ShiKey Laboratory of Artificial Structures and Quantum Control (Ministry of Education), Shenyang National Laboratory for Materials Science, School of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, China.ORCID 0000-0002-3928-2960
Shiyong WangKey Laboratory of Artificial Structures and Quantum Control (Ministry of Education), Shenyang National Laboratory for Materials Science, School of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, China.ORCID 0000-0001-6603-9926
Xiaoguo LiuSchool of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, China.ORCID 0000-0002-7834-399X
Jiang LiInstitute of Materiobiology, Department of Chemistry, College of Science, Shanghai University, Shanghai, China.
Lihua WangInstitute of Materiobiology, Department of Chemistry, College of Science, Shanghai University, Shanghai, China.
Ying ZhuInstitute of Materiobiology, Department of Chemistry, College of Science, Shanghai University, Shanghai, China. zhuying331@shu.edu.cn.ORCID 0000-0003-0418-919X
Jianlei ShenSchool of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, China. shenjianlei@sjtu.edu.cn.ORCID 0000-0001-6386-5640
Ben Zhong TangSchool of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong, Shenzhen, China. tangbenz@cuhk.edu.cn.ORCID 0000-0002-0293-964X
Chunhai FanSchool of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, China. fanchunhai@sjtu.edu.cn.ORCID 0000-0002-7171-7338

Funding

National Natural Science Foundation of China (National Science Foundation of China) 21834007National Natural Science Foundation of China (National Science Foundation of China) 21904087National Natural Science Foundation of China (National Science Foundation of China) 21991134National Natural Science Foundation of China (National Science Foundation of China) 91953106National Natural Science Foundation of China (National Science Foundation of China) 92056117National Natural Science Foundation of China (National Science Foundation of China) T2188102Natural Science Foundation of Shanghai (Natural Science Foundation of Shanghai Municipality) 20dz1101000Natural Science Foundation of Shanghai (Natural Science Foundation of Shanghai Municipality) 20dz1101001Natural Science Foundation of Shanghai (Natural Science Foundation of Shanghai Municipality) 20dz1101002Natural Science Foundation of Shanghai (Natural Science Foundation of Shanghai Municipality) 21QA1404800
6 · The paper itself

Abstract

Interfacing molecular machines to inorganic nanoparticles can, in principle, lead to hybrid nanomachines with extended functions. Here we demonstrate a ligand engineering approach to develop atomically precise hybrid nanomachines by interfacing gold nanoclusters with tetraphenylethylene molecular rotors. When gold nanoclusters are irradiated with near-infrared light, the rotation of surface-decorated tetraphenylethylene moieties actively dissipates the absorbed energy to sustain the photothermal nanomachine with an intact structure and steady efficiency. Solid-state nuclear magnetic resonance and femtosecond transient absorption spectroscopy reveal that the photogenerated hot electrons are rapidly cooled down within picoseconds via electron-phonon coupling in the nanomachine. We find that the nanomachine remains structurally and functionally intact in mammalian cells and in vivo. A single dose of near-infrared irradiation can effectively ablate tumours without recurrence in tumour-bearing mice, which shows promise in the development of nanomachine-based theranostics.

Indexed as

NanoparticlesNeoplasmsStilbenesAnimalsGoldMammalsMicePhototherapyGoldStilbenestetraphenylethylene

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.