Evidence map›Paper›PMID 37956533›Full record

ReviewCurrent opinion in cell biology2023

Exploring the dynamic behavior of leukocytes with zebrafish.

Cassia Michael, Sofia de Oliveira

Erratum issuedOpen access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. SubvertingBiology · 2024
    Review
  6. Inflammation in Development and Aging: Insights from the Zebrafish Model.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Cassia MichaelDepartment of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Sofia de OliveiraDepartment of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA; Department of Medicine (Hepatology), Albert Einstein College of Medicine, Bronx, NY, 10461, USA; Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, NY, 10461, USA; Montefiore-Einstein Comprehensive Cancer Research Center, Albert Einstein College of Medicine, Bronx, NY, 10461, USA; Cancer Dormancy Tumor Microenvironment Institute, Albert Einstein College of Medicine, Bronx, NY, 10461, USA; Einstein-Mount Sinai Diabetes Research Center, Albert Einstein College of Medicine, USA. Electronic address: sofia.deoliveira@einsteinmed.edu.
Albert Einstein College of Medicine · US

Funding

Cell migration and wound repairR35GM118027 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Anna Huttenlocher · 2016 to 2026
$7.5M
Training Program in Cellular and Molecular Biology and GeneticsT32GM145438 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI CHARLES C QUERY · 2023 to 2026
$2.4M
Neutrophils in polytrauma – from recruitment to phenotypic and functional reprogrammingR35GM147416 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SOFIA DE OLIVEIRA · 2022 to 2026
$2.3M
NIGMS NIH HHS R35 GM118027NIGMS NIH HHS R35 GM147416NIGMS NIH HHS T32 GM145438
6 · The paper itself

Abstract

Cell migration is a complex and intricate network of physical, chemical, and molecular events that ultimately leads to cell motility. This phenomenon is involved in both physiological and pathological processes such as proper immune and inflammatory responses. Dysregulation of cell migration machinery in immune cells can have a tremendous impact on the trajectory of inflammation, infection, and resolution. The small vertebrate, the zebrafish, has a remarkable capacity for genetic and pharmacological manipulation aligned to transparency that enables modulation and visualization of cell migration in vivo noninvasively. Such characteristics revolutionized the field of leukocyte biology, particularly neutrophils. In this review, we will focus on leukocyte migration and highlight findings made in the zebrafish that demonstrate how this small vertebrate system is a unique model to perform in vivo imaging and study mechanisms that regulate the dynamic behavior of immune cells in their native environment under homeostasis or upon challenge.

Indexed as

LeukocytesZebrafishAnimalsCell MovementInflammationNeutrophilsCell migrationNon-invasive imagingZebrafish

Identifiers

PMID37956533
PMCPMC10842401
OpenAlexW4388593767

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.