Evidence map›Paper›PMID 37956127›Full record

Trial reportCirculation2024

A Multicenter, Single-Blind, Randomized, Warfarin-Controlled Trial of Edoxaban in Patients With Chronic Thromboembolic Pulmonary Hypertension: KABUKI Trial.

Kazuya Hosokawa, Hiroko Watanabe, Yu Taniguchi, Nobutaka Ikeda, Takumi Inami, Satoshi Yasuda, Toyoaki Murohara, Masaru Hatano, Yuichi Tamura, Jun Yamashita and 11 more

Open access · hybridAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Direct Oral Anticoagulants in Chronic Thromboembolic Pulmonary Hypertension: First Meta-Analysis of Prospective Studies.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Chronic thromboembolic pulmonary disease.The European respiratory journal · 2024
    Review
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 14 institutions in 1 country.

Kazuya HosokawaFaculty of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (K.H., K.A.).
Hiroko WatanabeCenter for Clinical and Translational Research, Kyushu University Hospital, Fukuoka, Japan (H.W., Y.K., K. Todaka).ORCID 0009-0009-5904-0422
Yu TaniguchiDivision of Cardiovascular Medicine, Kobe University Hospital, Japan (Y.T.).ORCID 0000-0002-8430-2123
Nobutaka IkedaDivision of Cardiovascular Medicine, Toho University Medical Center Ohashi Hospital, Tokyo, Japan (N.I.).ORCID 0000-0002-1615-3736
Takumi InamiDepartment of Cardiovascular Medicine, Kyorin University School of Medicine, Tokyo, Japan (T.I.).
Satoshi YasudaDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan (S.Y., N.Y.).ORCID 0000-0002-7470-5236
Toyoaki MuroharaDepartment of Cardiology, Nagoya University Hospital, Japan (T.M, S.A.).ORCID 0000-0003-2723-6243
Masaru HatanoDepartment of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Japan (M.H., S.M.).ORCID 0000-0003-2135-3625
Yuichi TamuraPulmonary Hypertension Center, International University of Health and Welfare Mita Hospital, Tokyo, Japan (Y.T.).
Jun YamashitaDepartment of Cardiology, Tokyo Medical University, Japan (J.Y.).ORCID 0000-0002-0620-1685
Koichiro TatsumiDepartment of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan (K. Tatsumi).ORCID 0000-0001-9484-7912
Ichizo TsujinoDivision of Respiratory and Cardiovascular Innovative Research, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan (I.T.).ORCID 0000-0002-0196-9572
Yuko KobayakawaCenter for Clinical and Translational Research, Kyushu University Hospital, Fukuoka, Japan (H.W., Y.K., K. Todaka).ORCID 0000-0002-8422-1112
Shiro AdachiDepartment of Cardiology, Nagoya University Hospital, Japan (T.M, S.A.).ORCID 0000-0001-8924-1916
Nobuhiro YaoitaDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan (S.Y., N.Y.).ORCID 0000-0003-2667-8031
Shun MinatsukiDepartment of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Japan (M.H., S.M.).ORCID 0000-0002-9543-5503
Koji TodakaCenter for Clinical and Translational Research, Kyushu University Hospital, Fukuoka, Japan (H.W., Y.K., K. Todaka).
Keiichi FukudaDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan (K.F.).ORCID 0000-0003-1413-0482
Hiroyuki Tsutsui *International University of Health and Welfare, Okawa, Japan (H.T.).
Kohtaro Abe *Faculty of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (K.H., K.A.).
KABUKI Investigators
Kyushu University Hospital · JPKyushu University · JPNagoya University Hospital · JPThe University of Tokyo · JPTohoku University · JPChiba University · JPHokkaido University · JPInternational University of Health and Welfare · JPKeio University · JPKobe University Hospital · JPKyorin University · JPMita Hospital · JPToho University · JPTokyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hypertension, PulmonaryPyridinesThiazolesAnticoagulantsFactor Xa InhibitorsHumansSingle-Blind MethodTreatment OutcomeWarfarinAnticoagulantsedoxabanFactor Xa InhibitorsPyridinesThiazolesWarfarinanticoagulantsfactor Xa Inhibitorshypertension, pulmonaryrandomized controlled trialthromboembolismwarfarin

Identifiers

PMID37956127
PMCPMC10814998
OpenAlexW4388625516

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.