Evidence map›Paper›PMID 37955859›Full record

ArticleAdvanced biology2024

Microporous Annealed Particle (MAP) Scaffold Pore Size Influences Mesenchymal Stem Cell Metabolism and Proliferation Without Changing CD73, CD90, and CD105 Expression Over Two Weeks.

Blaise N Pfaff, Clare C Flanagan, Donald R Griffin

Abstract read
In one paragraph

Article in Advanced biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Metrics for studying the porous void space of packed particles.bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Blaise N PfaffUniversity of Virginia, 415 Lane Road, Charlottesville, VA, 22903, USA.
Clare C FlanaganUniversity of Virginia, 415 Lane Road, Charlottesville, VA, 22903, USA.
Donald R GriffinUniversity of Virginia, 415 Lane Road, Charlottesville, VA, 22903, USA.ORCID 0000-0002-3458-867X

Funding

BIOTECHNOLOGY TRAINING PROGRAMT32GM008715 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI LAURIE, GORDON WILLIAM · 2000 to 2019
$6.6M
Engineering Injectable Microporous Hydrogels for Diabetic Wound RepairR01DK126020 · NIDDK · UNIVERSITY OF VIRGINIA · PI GRIFFIN, DONALD RICHIERI · 2021 to 2025
$3.1M
Engineering Injectable Microporous Hydrogels for Diabetic Wound RepairR56DK126020 · NIDDK · UNIVERSITY OF VIRGINIA · PI GRIFFIN, DONALD RICHIERI · 2020 to 2020
$147k
NIDDK NIH HHS 1R56DK126020-01NIDDK NIH HHS R01 DK126020NIDDK NIH HHS R01DK126020NIDDK NIH HHS R56 DK126020NIGMS NIH HHS T32 GM008715NIH HHS T32GM008715
6 · The paper itself

Abstract

Scaffold pore architecture is shown to influence stem cell fate through various avenues. It is demonstrated that microporous annealed particle (MAP) microgel diameter can be tuned to control scaffold pore size and, in turn, modulate mesenchymal stem cell (MSC) survivability, proliferation, metabolism, and migration, thereby enhancing bioactivity and guiding future applications of MAP for regenerative medicine.

Indexed as

Mesenchymal Stem CellsTissue ScaffoldsCell DifferentiationCell ProliferationStem Cellsdifferentiationmesenchymal stem cellsmicroporous annealed particle scaffoldsporous scaffolds

Identifiers

PMID37955859
PMCPMC10922193

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.