Evidence map›Paper›PMID 37955768›Full record

ArticleBiological trace element research2024

Pancreatic Antioxidative Defense and Heat Shock Proteins Prevent Islet of Langerhans Cell Death After Chronic Oral Exposure to Cadmium LOAEL Dose.

Diana Moroni-González, Victor Enrique Sarmiento-Ortega, Alfonso Diaz, Eduardo Brambila, Samuel Treviño

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Diana Moroni-GonzálezLaboratory of Chemical-Clinical Investigations, Department of Clinical Chemistry, Chemistry Department, Meritorious Autonomous University of Puebla, 14 Sur. FCQ1, Ciudad Universitaria, 72560, Puebla, C.P, Mexico.
Victor Enrique Sarmiento-OrtegaLaboratory of Chemical-Clinical Investigations, Department of Clinical Chemistry, Chemistry Department, Meritorious Autonomous University of Puebla, 14 Sur. FCQ1, Ciudad Universitaria, 72560, Puebla, C.P, Mexico.ORCID https://orcid.org/0000-0003-4500-0648
Alfonso DiazDepartment of Pharmacy, Faculty of Chemistry Science, Meritorious Autonomous University of Puebla, 22 South, FCQ9, Ciudad Universitaria, 72560, Puebla, C.P, Mexico.ORCID https://orcid.org/0000-0002-7940-6059
Eduardo BrambilaLaboratory of Chemical-Clinical Investigations, Department of Clinical Chemistry, Chemistry Department, Meritorious Autonomous University of Puebla, 14 Sur. FCQ1, Ciudad Universitaria, 72560, Puebla, C.P, Mexico.ORCID https://orcid.org/0000-0003-4092-6636
Samuel TreviñoLaboratory of Chemical-Clinical Investigations, Department of Clinical Chemistry, Chemistry Department, Meritorious Autonomous University of Puebla, 14 Sur. FCQ1, Ciudad Universitaria, 72560, Puebla, C.P, Mexico. samuel.trevino@correo.buap.mx.ORCID https://orcid.org/0000-0001-5679-1671
Benemérita Universidad Autónoma de Puebla · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium, a hazardous environmental contaminant, is associated with metabolic disease development. The dose with the lowest observable adverse effect level (LOAEL) has not been studied, focusing on its effect on the pancreas. We aimed to evaluate the pancreatic redox balance and heat shock protein (HSP) expression in islets of Langerhans of male Wistar rats chronically exposed to Cd LOAEL doses, linked to their survival. Male Wistar rats were separated into control and cadmium groups (drinking water with 32.5 ppm CdCl

Indexed as

AntioxidantsCadmiumHeat-Shock ProteinsIslets of LangerhansRats, WistarAdministration, OralAnimalsCell DeathMalePancreasRatsAntioxidantsCadmiumHeat-Shock ProteinsCadmiumHeat shock proteinsLangerhans isletsOxidative stressPancreas

Identifiers

PMID37955768
OpenAlexW4388639462

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.