Evidence map›Paper›PMID 37955684›Full record

ArticleActa neurochirurgica2023

Microsurgical posterior fossa re-exploration for recurrent trigeminal neuralgia after previous microvascular decompression: common grounds-scarring, deformation, and the "piston effect".

Gökce Hatipoglu Majernik, Filipe Wolff Fernandes, Shadi Al-Afif, Hans E Heissler, Joachim K Krauss

Open access · hybridAbstract read
In one paragraph

Article in Acta neurochirurgica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Pathophysiology and Management of Refractory Trigeminal Neuralgia.Current neurology and neuroscience reports · 2024
    Review
  8. Article
  9. Modern Approaches to the Treatment of Acute Facial Pain.Current pain and headache reports · 2024
    Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gökce Hatipoglu MajernikDepartment of Neurosurgery, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Lower Saxony, Germany.
Filipe Wolff FernandesDepartment of Neurosurgery, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Lower Saxony, Germany. wolfffernandes.filipe@mh-hannover.de.ORCID 0000-0003-1201-7590
Shadi Al-AfifDepartment of Neurosurgery, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Lower Saxony, Germany.
Hans E HeisslerDepartment of Neurosurgery, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Lower Saxony, Germany.
Joachim K KraussDepartment of Neurosurgery, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Lower Saxony, Germany.
Medizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMicrovascular decompression (MVD) is a well-accepted treatment modality for trigeminal neuralgia (TN) with high initial success rates. The causes for recurrence of TN after previously successful MVD have not been fully clarified, and its treatment is still a matter of debate. Here, we present the surgical findings and the clinical outcome of patients with recurrent TN after MVD who underwent posterior fossa re-exploration.

methodsMicrosurgical posterior fossa re-exploration was performed in 26 patients with recurrent TN (mean age 59.1 years) who underwent MVD over a period of 10 years. The trigeminal nerve was exposed, and possible factors for recurrent TN were identified. Arachnoid scars and Teflon granulomas were dissected meticulously without manipulating the trigeminal nerve. Outcome of posterior fossa re-exploration was graded according to the Barrow Neurological Institute (BNI) pain intensity score. Follow-up was analyzed postoperatively at 3, 12, and 24 months and at the latest available time point for long-term outcome.

resultsThe mean duration of recurrent TN after the first MVD was 20 months. Pain relief was achieved in all patients with recurrent TN on the first postoperative day. Intraoperative findings were as follows: arachnoid scar tissue in 22/26 (84.6%) patients, arterial compression in 1/26 (3.8%), venous contact in 8/26 (30.8%), Teflon granuloma in 14/26 (53.8%), compression by an electrode in Meckel's cave used for treatment of neuropathic pain in 1/26 (3.8%), evidence of pulsations transmitted to the trigeminal nerve through the Teflon inserted previously/scar tissue ("piston effect") in 15/26 (57.7%), and combination of findings in 18/26 (69.2%). At long-term follow-up (mean 79.5 months; range, 29-184 months), 21/26 (80.8%) patients had favorable outcome (BNI I-IIIa). New hypaesthesia secondary to microsurgical posterior fossa re-exploration occurred in 5/26 (19.2%) patients.

conclusionsPosterior fossa re-exploration avoiding manipulation to the trigeminal nerve, such as pinching or combing, may be a useful treatment option for recurrent TN after previously successful MVD providing pain relief in the majority of patients with a low rate of new hypaesthesia.

Indexed as

Microvascular Decompression SurgeryTrigeminal NeuralgiaCicatrixHumansMiddle AgedNeoplasm Recurrence, LocalPainPolytetrafluoroethyleneRetrospective StudiesTreatment OutcomePolytetrafluoroethyleneJannettaMicrovascular decompressionRecurrenceTeflonTrigeminal neuralgia

Identifiers

PMID37955684
PMCPMC10739219
OpenAlexW4388626007

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.