Evidence map›Paper›PMID 37955550›Full record

ArticleEuropean journal of neurology2024

Is there a relationship between opioid use and transient global amnesia?

Jed A Barash, Megha Parikh, Rosa Ergas, Alfred DeMaria

Open access · hybridAbstract readComment
In one paragraph

Article in European journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jed A BarashVeterans' Home, Chelsea, Massachusetts, USA.ORCID 0009-0004-6361-6248
Megha ParikhMassachusetts Department of Public Health, Boston, Massachusetts, USA.
Rosa ErgasMassachusetts Department of Public Health, Boston, Massachusetts, USA.
Alfred DeMariaMassachusetts Department of Public Health, Boston, Massachusetts, USA.
Massachusetts Department of Public Health · USWisconsin Veterans Museum · US

Funding

CDC HHS NU17CE925012
6 · The paper itself

Abstract

background and purposeOpioid-associated amnestic syndrome (OAS) and transient global amnesia (TGA) are conditions with clinical overlap. We therefore sought to determine whether opioid use might be associated with TGA.

methodsData from the Massachusetts Department of Public Health Syndromic Surveillance program were queried to ascertain the frequency of opioid use among emergency department (ED) encounters for TGA compared to that for all other ED visits between January 2019 and June 2023.

resultsA total of 13,188,630 ED visits were identified during the study period. Of 1417 visits for TGA, one visit met the exposure definition for opioid use. There were 13,187,213 visits for other indications, 57,638 of which were considered opioid-exposed. The odds ratio for the relationship between opioid use and TGA was 0.16 (95% confidence interval 0.02, 1.14).

conclusionDespite the clinical overlap between OAS and TGA, surveillance data from ED visits in Massachusetts do not suggest that opioid use is a risk factor for TGA, indicating that OAS and TGA are distinct entities.

Indexed as

Amnesia, Transient GlobalAmnesiaAnalgesics, OpioidEmergency Service, HospitalHumansRisk FactorsAnalgesics, Opioidamnestic syndromeopioidtransient global amnesia

Identifiers

PMID37955550
PMCPMC11235587
OpenAlexW4388629480

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.