SynthesisRenal failure2023
Gastrointestinal bleeding in chronic kidney disease patients: a systematic review and meta-analysis.
Synthesis in Renal failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Pooled it
- Small Bowel Lesions and Bleeding Risk in Hemodialysis Patients: A Narrative Review.Hemodialysis international. International Symposium on Home Hemodialysis · 2026Review
- Article
- Article
- Development and internal validation of a machine learning-based model to predict 1-year all-cause mortality in patients with gastrointestinal bleeding with type 2 diabetes.BMC medical informatics and decision making · 2026Article
- Comparative Evaluation of A4C, CHAMPS, and CAGIB Scores for Risk Stratification in Hemodialysis Patients with Acute Gastrointestinal Bleeding.Diagnostics (Basel, Switzerland) · 2026Article
- Impact of End-Stage Renal Disease on Outcomes After Salvage Transcatheter Arterial Embolization for Duodenal Ulcer Bleeding.International journal of general medicine · 2026Article
- Endoscopic intervention for patients of renal insufficiency with upper gastrointestinal bleeding: efficacy evaluation and predictive model construction.BMC gastroenterology · 2025Article
- Risk of Post-polypectomy Bleeding After Colorectal Endoscopic Mucosal Resection in Patients with Chronic Kidney Disease: A Propensity-Matched Analysis of the US Collaborative Network.Digestive diseases and sciences · 2025Article
- Diagnostic value of the urea-to-creatinine ratio for gastrointestinal bleeding source: influence of renal function.BMC nephrology · 2025Article
- Clinical Outcomes of Iron Supplement Therapy in Non-Anemic Female CKD Stage 3 Patients with Low Serum Ferritin Level: A Multi-Institutional TriNetX Analysis.Journal of clinical medicine · 2025Article
- [Risk Factors for Mortality in Hemodialysis Patients With Gastrointestinal Bleeding].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Article
- Chronic Kidney Disease Increases Risk of Delayed Post-Polypectomy Bleeding: A Large-Scale Propensity Score-Matched Analysis.United European gastroenterology journal · 2025Article
- Incidence and Risk Factors of In-Hospital Gastrointestinal-Related Complications Following Bariatric Surgery: A Retrospective Nationwide Inpatient Sample Database Study.Obesity surgery · 2025Article
- Gastrointestinal disease in end-stage renal disease.World journal of nephrology · 2025Review
- Inpatient Outcomes of Gastrointestinal Bleeding in Advanced CKD and Kidney Transplant Recipients: A National Analysis 2016-2019.Kidney360 · 2025Article
- Article
- Renal dysfunction contributes to deteriorated survival outcomes in patients with upper and lower gastrointestinal bleeding: insights from a cohort study of 1160 cases.Scientific reports · 2025Article
- A predictive model for upper gastrointestinal bleeding in patients with acute myocardial infarction complicated by cardiogenic shock during hospitalization.Frontiers in cardiovascular medicine · 2025Article
- Anemia of Chronic Kidney Disease-A Narrative Review of Its Pathophysiology, Diagnosis, and Management.Biomedicines · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastrointestinal bleeding (GIB) is a major cause of mortality in patients with renal failure. We conducted a systematic review of the literature to evaluate the rates, predictors, and outcomes of GIB in patients with chronic kidney disease (CKD). A search of MEDLINE and EMBASE databases was performed, and data were extracted from relevant studies. Statistical pooling was performed to determine the rate of GIB in patients with CKD, and a random-effect meta-analysis was performed to determine the predictors of GIB and mortality in patients with GIB. Twenty-two studies were included in this review, with 7,810,273 patients with CKD included in the analysis. The pooled results of five studies suggested that the rate of GIB in patients with CKD was 2.2%, and among the studies in which patients with CKD underwent endoscopy, the pooled results for GIB were 35.8%. Receipt of dialysis (OR 14.48, 95%CI 4.96-42.32), older age (OR 1.03, 95%CI 1.02-1.05), diabetes mellitus (OR 1.30, 95%CI 1.22-1.39), history of ulcers (OR 1.53, 95%CI 1.03-2.26), and cirrhosis (OR 1.73, 95%CI 1.41-2.12) were significantly associated with GIB. The pooled results suggest a twofold increase in the odds of mortality with GIB, with significant heterogeneity (OR 2.12, 95%CI 1.45-3.10,
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.