Evidence map›Paper›PMID 37954834›Full record

ArticleJCEM case reports2023

Initiation of Continuous rhPTH Infusion With Insulin Pump in an Inpatient Setting.

Faith Lindsay Mart, Karen K Winer, Karla Johnson, Halley Wasserman

Open access · diamondAbstract readCase Reports
In one paragraph

Article in JCEM case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Faith Lindsay MartDivision of Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID https://orcid.org/0000-0001-5162-0988
Karen K WinerNational Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20817, USA.ORCID https://orcid.org/0000-0001-8261-5188
Karla JohnsonDivision of Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Halley WassermanDivision of Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID https://orcid.org/0000-0002-8309-6321
Cincinnati Children's Hospital Medical Center · USNational Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoparathyroidism is one of the few remaining hormonal insufficiencies not treated with replacement of its missing hormone. Conventional therapy involves multiple daily oral doses of calcium, active vitamin D, and magnesium, which is not only cumbersome for patients, but carries risk of nephrocalcinosis and is inadequate in patients with enteral malabsorption. Subcutaneous parathyroid hormone 1-34 (PTH[1-34]) has been tested as a hormonal replacement therapy for treatment of hypoparathyroidism. PTH(1-34) delivered by continuous infusion via insulin pump decreases or eliminates the need for oral medications, stabilizes serum and urine calcium at normal levels with minimal fluctuation, and significantly reduces PTH doses. In this case report, we describe the clinical application of PTH(1-34) via insulin pump in an adolescent with autoimmune polyendocrinopathy syndrome type 1 (APS1). Transition to a PTH pump reduced hospital admissions for calcium abnormalities and allowed our patient to discontinue all scheduled daily conventional therapy.

Indexed as

autoimmune polyendocrinopathy syndrome type 1autoimmune polyglandular syndrome type 1continuous PTH delivered by pumphypoparathyroidismrecombinant human parathyroid hormone

Identifiers

PMID37954834
PMCPMC10634629
OpenAlexW4388555141

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.