Evidence map›Paper›PMID 37954288›Full record

ArticleHeliyon2023

First identification of the SARS-COV-2/XBB.1.5 sublineage among indigenous COVID-19 cases through the influenza sentinel surveillance system in Niger.

Adamou Lagare, Martin Faye, Moussa Issa, Oumou Hamidou, Baruani Bienvenu, Abdoulkarim Mohamed, Balki Aoula, Katoumi Moumouni, Fatima Hassane, Younoussa Adamou Otto and 5 more

Abstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Adamou LagareCentre de Recherche Médicale et Sanitaire (CERMES), 634 Bd de la Nation, Niamey, YN034, Niger.
Martin FayeVirology Department, Institut Pasteur de Dakar, 36, Avenue Pasteur Dakar, 220, Dakar, Senegal.
Moussa IssaCentre de Recherche Médicale et Sanitaire (CERMES), 634 Bd de la Nation, Niamey, YN034, Niger.
Oumou HamidouCentre de Recherche Médicale et Sanitaire (CERMES), 634 Bd de la Nation, Niamey, YN034, Niger.
Baruani BienvenuWorld Health Organization-Country Office, Boulevard Du Roi Mohamed 6, BP 10739, Niamey, Niger.
Abdoulkarim MohamedMinistère de la Santé Publique, BP:623, Niamey, Niger.
Balki AoulaCentre de Recherche Médicale et Sanitaire (CERMES), 634 Bd de la Nation, Niamey, YN034, Niger.
Katoumi MoumouniMinistère de la Santé Publique, BP:623, Niamey, Niger.
Fatima HassaneCentre de Recherche Médicale et Sanitaire (CERMES), 634 Bd de la Nation, Niamey, YN034, Niger.
Younoussa Adamou OttoCentre de Recherche Médicale et Sanitaire (CERMES), 634 Bd de la Nation, Niamey, YN034, Niger.
Didier D K TambweWorld Health Organization-Country Office, Boulevard Du Roi Mohamed 6, BP 10739, Niamey, Niger.
Elh Ibrahim TassiouMinistère de la Santé Publique, BP:623, Niamey, Niger.
Haoua SeiniCentre de Recherche Médicale et Sanitaire (CERMES), 634 Bd de la Nation, Niamey, YN034, Niger.
Ousmane FayeVirology Department, Institut Pasteur de Dakar, 36, Avenue Pasteur Dakar, 220, Dakar, Senegal.
Ronan JambouCentre de Recherche Médicale et Sanitaire (CERMES), 634 Bd de la Nation, Niamey, YN034, Niger.

Funding

World Health Organization 001
6 · The paper itself

Abstract

The emergence of the Omicron variant in November 2021, has caused panic worldwide due to the rapid evolution and the ability of the virus to escape the immune system. Since, several Omicron sublineages (BA.1 to BA.5) and their descendent recombinant lineages have been circulating worldwide. Furthermore, in December 2022, a new Omicron subvariant XBB.1.5 characterized by an unusual mutation in the spike protein evolved in the United States and rapidly spread to the other continents. Our study reports on the first cases of XBB.1.5 sublineage among indigenous Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2) positive cases detected through the influenza sentinel surveillance system in Niger. All influenza suspected cases were tested for both influenza and SARS-COV-2 using the Centre for Disease Control and prevention (CDC) Influenza SARS-COV-2 Multiplex quantitative Reverse-Transcription Polymerase Chain Reaction (qRT-PCR) Assay. SARS-COV-2 positive samples with cycle threshold ≤28 were selected for whole genome sequencing subsequently using the Oxford Nanopore Midnight protocol with rapid barcoding on a MinIon MK1B device. A total of 51 SARS-COV-2 positive samples were confirmed between December 2022 and March 2023. We successfully obtained 19 sequences with a predominance of the XBB.1/XBB.1.5 sublineages (73.7 %). In addition, a recombinant XBD sequence was also first-ever identified in early March 2023. Our findings support the need to strengthen the influenza sentinel surveillance for routine Coronavirus Disease 2019 (COVID-19) surveillance and SARS-COV-2 variants monitoring in Niger.

Indexed as

Influenza sentinel surveillance systemNigerSevere acute respiratory syndrome Coronavirus-2XBB.1.5 sublineage

Identifiers

PMID37954288
PMCPMC10637901

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.