Evidence map›Paper›PMID 37953978›Full record

ArticlePatient preference and adherence2023

Significance of Self-Injectable Biologics in Japanese Patients with Severe Allergic Diseases: Focusing on Pen-Type Devices and Copayment.

Soichiro Hanada, Masato Muraki, Yoshiyuki Kawabata, Kazuya Yoshikawa, Toshiyuki Yamagata, Tadao Nagasaki, Yushiro Ohara, Naoki Oiso, Hisako Matsumoto, Yuji Tohda

Open access · goldAbstract read
In one paragraph

Article in Patient preference and adherence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Soichiro Hanada *Department of Respiratory Medicine and Allergology, Kindai University Nara Hospital, Ikoma, Nara, Japan.ORCID 0009-0007-1356-5763
Masato Muraki *Department of Respiratory Medicine and Allergology, Kindai University Nara Hospital, Ikoma, Nara, Japan.
Yoshiyuki KawabataDepartment of Respiratory Medicine and Allergology, Kindai University Nara Hospital, Ikoma, Nara, Japan.
Kazuya YoshikawaDepartment of Respiratory Medicine and Allergology, Kindai University Nara Hospital, Ikoma, Nara, Japan.
Toshiyuki YamagataDepartment of Respiratory Medicine and Allergology, Kindai University Nara Hospital, Ikoma, Nara, Japan.
Tadao NagasakiDepartment of Respiratory Medicine and Allergology, Kindai University Nara Hospital, Ikoma, Nara, Japan.ORCID 0000-0002-3231-7841
Yushiro OharaDepartment of Dermatology, Kindai University Nara Hospital, Ikoma, Nara, Japan.
Naoki OisoDepartment of Dermatology, Kindai University Nara Hospital, Ikoma, Nara, Japan.
Hisako MatsumotoDepartment of Respiratory Medicine and Allergology, Kindai University Hospital, Osakasayama, Osaka, Japan.
Yuji TohdaKindai University Hospital, Osakasayama, Osaka, Japan.
Kindai University · JPKindai University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients and Methods: A questionnaire survey was administered to 18, 14, and 3 patients introduced to home self-injection of dupilumab or mepolizumab using a pen-type device for atopic dermatitis, asthma alone, and asthma plus chronic rhinosinusitis with nasal polyps, respectively. Results: All but one participant wished to continue self-injection. Most participants affirmed the reduction in copayment (88.6%) and saving time and labor for hospital visits (88.6%). Six patients who received dupilumab complained of side effects, but all, except for one, continued the treatment. Of the 13 patients who had previously used a syringe-type device, 10 preferred the pen type because of its ease of use, while 3 (23%) preferred the syringe type because of the self-adjustable injection speed for pain control. Conclusion: Administration of biologics using pen-type devices is easier, and the introduction of home self-injection leads to a reduction in outpatient visits and copayment.

Indexed as

asthmaatopic dermatitischronic sinusitis with nasal polypsdupilumabmepolizumabself-injection

Identifiers

PMID37953978
PMCPMC10638892
OpenAlexW4388456414

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.