Evidence map›Paper›PMID 37953958›Full record

ArticleiScience2023

Single-cell RNA sequencing of murine ankle joints over time reveals distinct transcriptional changes following

Jennifer D Helble, Michael J Walsh, Julie E McCarthy, Neal P Smith, Alice J Tirard, Benjamin Y Arnold, Alexandra-Chloe Villani, Linden T Hu

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Strain-specific immune response patterns toInfection and immunity · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Hitchhiker's Guide toJournal of bacteriology · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jennifer D HelbleDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111, USA.
Michael J WalshDivision of Gastroenterology, Massachusetts General Hospital, Boston, MA 02114, USA.
Julie E McCarthyDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111, USA.
Neal P SmithDepartment of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Alice J TirardDepartment of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Benjamin Y ArnoldDepartment of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Alexandra-Chloe VillaniDepartment of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Linden T HuDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111, USA.
Massachusetts General Hospital · USTufts University · US

Funding

Coping with Stress: Next Generation Approaches to Borrelia burgdorferi Host AdaptationR01AI131656 · NIAID · TUFTS UNIVERSITY BOSTON · PI HU, LINDEN T, SKARE, JON T · 2017 to 2021
$3.3M
Role of human innate immune mutations in loss of tolerance to Borrelia burgdorferiR01AI150157 · NIAID · TUFTS UNIVERSITY BOSTON · PI HU, LINDEN T · 2020 to 2024
$3.0M
NIAID NIH HHS R01 AI131656NIAID NIH HHS R01 AI150157
6 · The paper itself

Abstract

Lyme disease is caused by the bacterial pathogen

Indexed as

Cell biologyImmunologyMicrobiologyTranscriptomics

Identifiers

PMID37953958
PMCPMC10632114
OpenAlexW4387641077

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.