Evidence map›Paper›PMID 37953890›Full record

ArticleClinical case reports2023

Case report: Coexistence of Jacobs syndrome, congenital adrenal hyperplasia, and ambiguous genitalia in a male infant.

Qaisar Ali Khan, Faiza Amatul-Hadi, Amritpal Kooner, Amber Lee, Rahma Ahmed, Adithya Nadella, Harshawardhan Pande, Yaxel Levin-Carrion, Muhammad Afzal, Moses Alfaro

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PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 10 institutions in 4 countries.

Qaisar Ali KhanKhyber Teaching Hospital MTI KTH Peshawar Pakistan.ORCID https://orcid.org/0000-0001-8660-9551
Faiza Amatul-HadiMercer University School of Medicine Macon Georgia USA.
Amritpal KoonerChicago College of Osteopathic Medicine Downers Grove Illinois USA.
Amber LeeArkansas College of Osteopathic Medicine Fort Smith Arkansas USA.
Rahma AhmedKennesaw State University Kennesaw Georgia USA.
Adithya NadellaNanjing Medical University Nanjing China.
Harshawardhan PandeSaint Louis University St. Louis Missouri USA.
Yaxel Levin-CarrionRutgers New Jersey Medical School Newark New Jersey USA.ORCID https://orcid.org/0009-0002-7299-9741
Muhammad AfzalSt. George's University School of Medicine True Blue Grenada.ORCID https://orcid.org/0009-0005-5280-3862
Moses AlfaroLong School of Medicine at the University of Texas Health Science Center San Antonio San Antonio Texas USA.
American Osteopathic Association · USKennesaw State University · USKhyber Teaching Hospital · PKMercer University · USNanjing Medical University · CNRutgers, The State University of New Jersey · USSaint Louis University · USSt. George's University · GDThe University of Texas Health Science Center at San Antonio · USUniversity of Arkansas – Fort Smith · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Key Clinical Message: Jacobs syndrome and congenital adrenal hyperplasia are separate entities but share common clinical features such as ambiguous genitalia. Further studies are needed to conclude the relationship between Jacobs syndrome and congenital adrenal hyperplasia. Abstract: A 5-month-old male infant was evaluated for ambiguous genitalia. Examination revealed cryptorchidism, inguinal hernia, long phallus, and Grade 3 scrotal hypospadias. Serum 17-OH progesterone was high and chromosomal analysis showed 47XYY/45XO. A diagnosis of Jacobs and CAH was made. The parents were counseled about the patient's condition. He was given hydrocortisone and referred to the pediatric surgeon for further management.

Indexed as

congenital adrenal hyperplasiaJacobs syndromevirilizationXY karyotype

Identifiers

PMID37953890
PMCPMC10636557
OpenAlexW4388570715

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.