Evidence map›Paper›PMID 37953856›Full record

ArticleClinical, cosmetic and investigational dermatology2023

Characterization of Epidermal Function in Individuals with Primary Cutaneous Amyloidosis.

Fujuan Huang, Yuling Zhang, Junyi Guo, Hongju Pan, Zhigang Liao, Bin Yang, Ping Lu

Abstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fujuan Huang *Department of Dermatology, Dermatology Hospital of Southern Medical University, Guangzhou, People's Republic of China.
Yuling Zhang *Department of Dermatology, The First Hospital of Jilin University, Changchun, People's Republic of China.
Junyi GuoDepartment of Dermatology, Guangdong Provincial Dermatology Hospital, Guangzhou, People's Republic of China.
Hongju PanGuangdong Provincial Engineering Technology Research and Development Center for External Drugs, Foshan, People's Republic of China.
Zhigang LiaoGuangdong Provincial Engineering Technology Research and Development Center for External Drugs, Foshan, People's Republic of China.
Bin YangDepartment of Dermatology, Dermatology Hospital of Southern Medical University, Guangzhou, People's Republic of China.ORCID 0000-0002-7155-6079
Ping LuDepartment of Dermatology, Dermatology Hospital of Southern Medical University, Guangzhou, People's Republic of China.ORCID 0000-0002-3787-4495

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To compare epidermal biophysical properties, indicators of epidermal function, in individuals with and without primary cutaneous amyloidosis (PCA). Patients and Methods: This study incorporated 189 patients with PCA and 166 healthy individuals. The GPSkin Barrier was employed to measure transepidermal water loss (TEWL) rates and hydration levels of the stratum corneum. The Sebumeter and the Skin pH Meter were utilized to determine the skin surface's sebum content and pH, respectively. The severity of pruritus in participants was evaluated using the visual analog scale (VAS). Results: Compared to the control group without PCA, individuals with PCA displayed a notable increase in skin surface pH and TEWL and a decrease in the hydration levels of the stratum corneum ( Conclusion: The function of the epidermis is compromised in individuals diagnosed with PCA. However, the mechanisms underlying these changes await further investigation.

Indexed as

biophysical propertiescutaneous amyloidosisepidermispruritus

Identifiers

PMID37953856
PMCPMC10637218

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.