Evidence map›Paper›PMID 37953819›Full record

ArticleOpen forum infectious diseases2023

Short-Course Versus Prolonged-Course Antimicrobial Therapy in Adults With Catheter-Related Septic Thrombosis: A Propensity-Weighted Retrospective Study.

Marine Stoldick, Margot Vannier, Mikael Verdalle-Cazes, Manuel Etienne, Kévin Alexandre

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marine StoldickDepartment of Infectious Diseases, Centre hospitalier universitaire Rouen, Rouen, France.
Margot VannierDepartment of Biostatistics, Centre hospitalier universitaire Rouen, Rouen, France.
Mikael Verdalle-CazesDepartment of Radiology, Centre hospitalier universitaire Rouen, Rouen, France.
Manuel EtienneUniv Rouen Normandie, Université de Caen, INSERM, Normandie Univ, DYNAMICURE Unité mixte de recherche 1311, Centre hospitalier universitaire Rouen, Department of Infectious Diseases, Rouen, France.ORCID https://orcid.org/0000-0002-7301-2614
Kévin AlexandreUniv Rouen Normandie, Université de Caen, INSERM, Normandie Univ, DYNAMICURE Unité mixte de recherche 1311, Centre hospitalier universitaire Rouen, Department of Infectious Diseases, Rouen, France.ORCID https://orcid.org/0000-0001-7773-5695
Centre Hospitalier Universitaire de Rouen · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Optimal duration of antimicrobial therapy (AT) for catheter-related septic deep venous thrombosis (DVT) is unknown. We aimed to compare the outcomes of patients receiving short-course AT (≤21 days) versus prolonged-course AT (>21 days). Methods: This was a monocentric retrospective study comparing adults with catheter-related septic DVT from 2015 to 2020 treated with short- or prolonged-course AT. A propensity score-weighted analysis was used to mitigate potential bias. The primary outcome was a composite of all-cause mortality or recurrent bloodstream infection 30 days after AT discontinuation. Results: Of 172 patients with catheter-related septic DVT, 104 were treated with prolonged-course AT and 68 with short-course AT. In the propensity score analysis, we found no significant difference in 30-day all-cause mortality or relapse between the 2 groups (inverse probability of treatment weighted hazard ratio [wHR], 2.16 [95% confidence interval {CI}, .68-6.88]; Conclusions: A 21-day AT could be an effective and safe option to treat catheter-related septic DVT. Further randomized studies are needed to establish the optimal duration of AT for patients with catheter-related septic DVT.

Indexed as

catheter-related infectiondurationseptic thrombosisshort-course therapy

Identifiers

PMID37953819
PMCPMC10638491
OpenAlexW4387933430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.