Evidence map›Paper›PMID 37953780›Full record

ArticlePeerJ2023

AL360181.1 promotes proliferation and invasion in colon cancer and is one of ten m6A-related lncRNAs that predict overall survival.

Yi Luo, Yayun Xie, Dejun Wu, Bingyi Wang, Helei Lu, Zhiqiang Wang, Yingjun Quan, Bo Han

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yi Luo *Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yayun Xie *Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Dejun WuShanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China.
Bingyi WangTongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Helei LuTongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhiqiang WangTongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yingjun QuanTongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Bo HanTongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Jiao Tong University · CNTongren Hospital · CNFudan University · CN

Funding

Biomedical Data Translator Technical Feasibility Assessment and Architecture DesignOT3TR002020 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AHALT, STANLEY CARLTON, TROPSHA, ALEXANDER · 2016 to 2019
$3.1M
NCATS NIH HHS OT3 TR002020
6 · The paper itself

Abstract

Background: N6-methyladenosine (m6A) exerted a pivotal role in colon cancer. Nevertheless, the long non-coding RNAs (lncRNAs) associated with this process have yet to be elucidated. Methods: The open-access data used for analysis was downloaded from The Cancer Genome Atlas (TCGA) database for analysis, employing the R software for computational evaluations. The RNA level of specific molecules was assessed using the quantitative real-time PCR. CCK8, colony formation and transwell assay were used to evaluate the proliferation, invasion and migration ability of colon cancer cells. Results: Here, we identified the m6A regulators from TCGA data and subsequently pinpointed lncRNAs with a -Cor- > 0.3 and Conclusions: Our results can provide direction for future studies on m6A-related lncRNA in colon cancer.

Indexed as

Colonic NeoplasmsRNA, Long NoncodingCell ProliferationHedgehog ProteinsHumansHedgehog ProteinsRNA, Long NoncodingAL360181.1Colon cancerGlycolysisImmuneM6APrognosis

Identifiers

PMID37953780
PMCPMC10638913
OpenAlexW4388553668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.