Evidence map›Paper›PMID 37953410›Full record

ArticleJournal of anatomy2024

Intracortical remodelling increases in highly loaded bone after exercise cessation.

Raniere Gaia Costa da Silva, Tsim Christopher Sun, Ambika Prasad Mishra, Alan Boyde, Michael Doube, Christopher Michael Riggs

Abstract read
In one paragraph

Article in Journal of anatomy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Raniere Gaia Costa da SilvaDepartment of Infectious Diseases and Public Health, City University of Hong Kong, Kowloon, Hong Kong.ORCID 0000-0002-8381-3749
Tsim Christopher SunSydney School of Veterinary Science, University of Sydney, Camperdown, New South Wales, Australia.ORCID 0000-0003-1033-8251
Ambika Prasad MishraDepartment of Infectious Diseases and Public Health, City University of Hong Kong, Kowloon, Hong Kong.ORCID 0000-0002-0942-0787
Alan BoydeBarts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID 0000-0002-9871-5498
Michael DoubeDepartment of Infectious Diseases and Public Health, City University of Hong Kong, Kowloon, Hong Kong.ORCID 0000-0002-8021-8127
Christopher Michael RiggsEquine Welfare Research Foundation, The Hong Kong Jockey Club, Sha Tin, Hong Kong.ORCID 0000-0002-9332-4789

Funding

Arthritis Research UK
6 · The paper itself

Abstract

Resorption within cortices of long bones removes excess mass and damaged tissue and increases during periods of reduced mechanical loading. Returning to high-intensity exercise may place bones at risk of failure due to increased porosity caused by bone resorption. We used point-projection X-ray microscopy images of bone slices from highly loaded (metacarpal, tibia) and minimally loaded (rib) bones from 12 racehorses, 6 that died during a period of high-intensity exercise and 6 that had a period of intense exercise followed by at least 35 days of rest prior to death, and measured intracortical canal cross-sectional area (Ca.Ar) and number (N.Ca) to infer remodelling activity across sites and exercise groups. Large canals that are the consequence of bone resorption (Ca.Ar >0.04 mm

Indexed as

Bone RemodelingBone ResorptionAnimalsOsteogenesisRibsTibiaboneexerciseresorptionrest

Identifiers

PMID37953410
PMCPMC10862154

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.