Evidence map›Paper›PMID 37953405›Full record

ArticleOrthopaedic surgery2024

Race and Gender Differences in Anterior Cruciate Ligament Femoral Footprint Location and Orientation: A 3D-MRI Study.

Lihang Zhang, Tianwen Huang, Changzhao Li, Xing Xing, Diyang Zou, Dimitris Dimitriou, Tsung-Yuan Tsai, Pingyue Li

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Article in Orthopaedic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Lihang ZhangGuangdong Key Lab of Orthopedic Technology and Implant, General Hospital of Southern Theater Command of PLA, The First School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Tianwen HuangGuangdong Key Lab of Orthopedic Technology and Implant, General Hospital of Southern Theater Command of PLA, The First School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Changzhao LiGuangdong Key Lab of Orthopedic Technology and Implant, General Hospital of Southern Theater Command of PLA, The First School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Xing XingSchool of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Diyang ZouEngineering Research Center of Digital Medicine and Clinical Translation, Ministry of Education, Shanghai, China.
Dimitris DimitriouDepartment of Orthopedics, University Hospital Balgrist, Zurich, Switzerland.
Tsung-Yuan TsaiEngineering Research Center of Digital Medicine and Clinical Translation, Ministry of Education, Shanghai, China.
Pingyue LiGuangdong Key Lab of Orthopedic Technology and Implant, General Hospital of Southern Theater Command of PLA, The First School of Clinical Medicine, Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0003-0863-8204

Funding

Fundamental Research Funds for the Central Universities AF0820060Military Project of Application Fundamentals 20QNPY084Military Project of Application Fundamentals 21FYFH06Military Project of Application Fundamentals CLB18J037Military Project of Application Fundamentals CLB21J021National Natural Science Foundation of China 31972924National Natural Science Foundation of China 81871808Pudong New Area Science & Technology Development Fund 210H1147900"Science and Technology Innovation Action Plan" of Science and Technology Commission of Shanghai Municipality 21DZ2208200"Science and Technology Innovation Action Plan" of Science and Technology Commission of Shanghai Municipality 22S31906000"Science and Technology Innovation Action Plan" of Science and Technology Commission of Shanghai Municipality 23S31901000
6 · The paper itself

Abstract

objectiveThe femoral tunnel position is crucial to anatomic single-bundle anterior cruciate ligament (ACL) reconstruction, but the ideal femoral footprint position are mostly based on small-sized cadaveric studies and elderly patients with a single ethnic background. This study aimed to identify potential race- or gender-specific differences in the ACL femoral footprint location and ACL orientation, determine the correlation between the ACL orientation and the femoral footprint location.

methodsMagnetic resonance images (MRIs) of 90 Caucasian participants and 90 matched Chinese subjects were used for reconstruction of three-dimensional (3D) femur and tibial models. ACL footprints were sketched by several experienced orthopedic surgeons on the MRI photographs. The anatomical coordinate system was applied to reflect the ACL footprint location and orientation of scanned samples. The femoral ACL footprint locations were represented by their distance from the origin in the anteroposterior (A/P) and distal-proximal (D/P) directions. The orientation of the ACL was described with the sagittal, coronal and transverse deviation angles. The ACL orientation and femoral footprint position were compared by the two-sided t-test. Multiple regression analysis was used to study the correlation between the orientation and femoral footprint position.

resultsThe average femur footprint A/P position was -6.6 ± 1.6 mm in the Chinese group and -5.1 ± 2.3 mm in the Caucasian group, (p < 0.001). The average femur footprint D/P position was -2.8 ± 2.4 mm in Chinese and - 3.9 ± 2.0 mm in Caucasians, (p = 0.001). The Chinese group had a mean difference of a 1.5 mm (6.1%) more posterior and 1.1 mm (5.3%) more proximal in the position from the flexion-extension axis (FEA). And the males have a sagittal plane elevation about 4-5° higher than females in both racial groups. Furthermore, for every 1% (0.40 mm) increase in A/P and D/P values, the sagittal angle decreased by about 0.12° and 0.24°, respectively; the coronal angle decreased by about 0.10° and 0.30°, respectively. For every 1% (0.40 mm) increase in D/P value, the transverse angle increased by about 0.14°.

conclusionThe significant race- and gender-specific differences in the femoral footprint and orientation of the ACL should be taken in consideration during anatomic single-bundle ACL reconstruction. Furthermore, the quantitative relationship between the ACL orientation and the footprint location might provide some reference for surgeons to develop a surgical strategy in ACL single-bundle reconstruction and revision.

Indexed as

Anterior Cruciate LigamentKnee JointAgedFemaleFemurHumansMagnetic Resonance ImagingMaleSex FactorsTibiaAnatomical single-bundle reconstructionAnterior cruciate ligamentEthnicityFemoral footprintsGenderOrientation of ligament

Identifiers

PMID37953405
PMCPMC10782238

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.