Evidence map›Paper›PMID 37952231›Full record

Trial reportEuropean journal of applied physiology2024

Comparison of neuromuscular fatigability amplitude and etiologies between fatigued and non-fatigued cancer patients.

M Chartogne, A Rahmani, S Landry, B Morel

Registry-linked trialAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04391543 (BIOpsychosocial Approach of the CAncer-RElated FAtigue), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04391543 naunknown statusnot on this map

BIOpsychosocial Approach of the CAncer-RElated FAtigue

TypeinterventionalSponsorLe Mans UniversiteRan2021 to 2025Enrolled86ConditionsBreast CancerArmsExperimental session
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

M ChartogneLe Mans University, Movement-Interactions-Performance, MIP, UR 4334, 72000, Le Mans, France. martin.chartogne@univ-nantes.fr.ORCID http://orcid.org/0000-0002-9353-6677
A RahmaniLe Mans University, Movement-Interactions-Performance, MIP, UR 4334, 72000, Le Mans, France.
S LandryCentre de Cancérologie de la Sarthe, 72000, Le Mans, France.
B MorelLe Mans University, Movement-Interactions-Performance, MIP, UR 4334, 72000, Le Mans, France.
Le Mans Université · FRCentre Hospitalier du Mans · FRUniversité Nantes Angers Le Mans · FR

Funding

Conseil Régional des Pays de la Loire BIOCARE FActory projectLigue Contre le Cancer Thesis scholarship
6 · The paper itself

Abstract

purposeCancer-related fatigue (CRF) is the most reported side effect of cancer and its treatments. Mechanisms of CRF are multidimensional, including neuromuscular alterations leading to decreased muscle strength and endurance (i.e., fatigability). Recently, exercise fatigability and CRF have been related, while fatigability mechanisms remain unclear. Traditionally, fatigability is assessed from maximal voluntary contractions (MVC) decrease, but some authors hypothesized that the rate of force development (RFD) determined during a rapid contraction could also be an interesting indicator of functional alterations. However, to our knowledge, no study investigated RFD in cancer patients. The purpose of this study was to determine whether RFD, fatigability amplitude, and etiology are different between fatigued and non-fatigued cancer patients.

methodsEighteen participants with cancer, divided in fatigued or non-fatigued groups according their CRF level, completed a 5-min all-out exercise in ankle plantar flexor muscles composed of 62 isometric MVC of 4 s with 1 s rest, to assess fatigability amplitude as the force-time relationship asymptote (F

resultsF

conclusionDuring treatments, fatigability is higher in fatigued patients; however, the mechanisms of fatigability and RFD alterations are similar in both groups.

trial registrationClinicalTrials.gov, NCT04391543, May 2020.

Indexed as

Muscle FatigueNeoplasmsElectromyographyFatigueHumansIsometric ContractionMuscle ContractionMuscle, SkeletalCancerCancer-related fatigueForce–time asymptoteNeuromuscular fatigabilityTwitch interpolation technique

Identifiers

PMID37952231
OpenAlexW4388609325

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.