ArticleEuropean heart journal2024
Cardiovascular hospitalizations and mortality among adults aged 25-64 years in the USA.
Article in European heart journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Cardiometabolic health of low- and higher-income adults in the United States, 2009-2023.American heart journal · 2026Article
- Acute Myocardial Infarction in Medicare Beneficiaries During and After the COVID-19 Pandemic.JAMA network open · 2026Article
- Past, Present and Future of Regenerative Gene Therapy for Ischemic Heart Failure.Journal of cardiovascular translational research · 2026Review
- Out-of-Pocket Costs and Financial Burden Among Working-Age Adults With Cardiovascular Conditions: A JACC Data Report on Trends in the United States, 2007-2022.Journal of the American College of Cardiology · 2026Article
- Sex Differences in Outcomes of Young Adults Hospitalized With First Myocardial Infarction From 2011 to 2022.Journal of the American Heart Association · 2026Article
- Wildfire smoke PMScience advances · 2026Article
- Utilization and spending on lipid lowering therapies in medicaid from 2018 to 2022.American heart journal · 2025Article
- The association between triglyceride-glucose index and the recurrence of myocardial infarction in young patients with previous coronary heart disease.Scientific reports · 2025Article
- Marginalized Neighborhoods and Health Outcomes in Younger Myocardial Infarction Survivors.JAMA network open · 2025Article
- Association of biological aging acceleration transitions and burdens with incident cardiovascular disease: longitudinal insights from a national cohort study.BMC medicine · 2025Article
- Vitamin D status, vitamin D receptor polymorphisms, and risk of cardiometabolic multimorbidity.Nutrition journal · 2025Article
- Rural-Urban Differences in Cardiovascular Mortality in the United States, 2010-2022.Journal of the American College of Cardiology · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
Abstract
BACKGROUND AND
aimsDeclines in cardiovascular mortality have stagnated in the USA since 2011. There is growing concern that these patterns reflect worsening cardiovascular health in younger adults. However, little is known about how the burden of acute cardiovascular hospitalizations and mortality has changed in this population. Changes in cardiovascular hospitalizations and mortality among adults aged 25-64 years were evaluated, overall and by community-level income.
methodsUsing the National Inpatient Sample, age-standardized annual hospitalization and in-hospital mortality rates for acute myocardial infarction (AMI), heart failure, and ischaemic stroke were determined among adults aged 25-64 years. Quasi-Poisson and quasi-binominal regression models were fitted to compare outcomes between individuals residing in low- and higher-income communities.
resultsBetween 2008 and 2019, age-standardized hospitalization rates for AMI increased among younger adults from 155.0 (95% confidence interval: 154.6, 155.4) per 100 000 to 160.7 (160.3, 161.1) per 100 000 (absolute change +5.7 [5.0, 6.3], P < .001). Heart failure hospitalizations also increased (165.3 [164.8, 165.7] to 225.3 [224.8, 225.8], absolute change +60.0 (59.3, 60.6), P < .001), as ischaemic stroke hospitalizations (76.3 [76.1, 76.7] to 108.1 [107.8, 108.5], absolute change +31.7 (31.2, 32.2), P < .001). Across all conditions, hospitalizations rates were significantly higher among younger adults residing in low-income compared with higher-income communities, and disparities did not narrow between groups. In-hospital mortality decreased for all conditions over the study period.
conclusionsThere was an alarming increase in cardiovascular hospitalizations among younger adults in the USA from 2008 to 2019, and disparities between those residing in low- and higher-income communities did not narrow.
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