ArticleEye (London, England)2024
Detection and agreement of event-based OCT and OCTA analysis for glaucoma progression.
Article in Eye (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Automated Assessment of OCT Angiography Image Quality Using the Artificial Intelligence Ready and Exploratory Atlas for Diabetes Insights Data Set.Ophthalmology science · 2026Article
- Physical Activity and Macular Choroidal Circulation in Older Adults With Primary Open-Angle Glaucoma: A Swept-Source Optical Coherence Tomography Angiography Study.Translational vision science & technology · 2026Article
- Sleep Pattern and Structural Damage in Older Adults with Glaucoma: A United States and China Study.Ophthalmology science · 2026Article
- The Eye and the Brain: Photonic Devices in Neuro-Ophthalmology.Diseases (Basel, Switzerland) · 2026Review
- Retinomics as a Tool for Glaucoma Prediction.Ophthalmology science · 2026Article
- Glaucoma Progression Detection Time Using OCT and OCTA in African and European Descendants.American journal of ophthalmology · 2026Article
- Vascular Density and Retinal Structure Relationships Across Sectors and Regions of the Optic Nerve in Patients With Primary Open Angle Glaucoma.Journal of glaucoma · 2025Article
- Optical coherence tomography angiography compared with optical coherence tomography for detection of glaucoma progression with high myopia.Scientific reports · 2025Article
- A scoping review of advancements in machine learning for glaucoma: current trends and future direction.Frontiers in medicine · 2025Article
- Diagnostic Capability of OCTA-Derived Macular Biomarkers for Early to Moderate Primary Open Angle Glaucoma.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveTo examine event-based glaucoma progression using optical coherence tomography (OCT) and OCT angiography (OCTA).
methodsIn this retrospective study, glaucoma eyes with ≥2-year and 4-visits of OCT/OCTA imaging were included. Peripapillary capillary density (CD) and retinal nerve fibre layer thickness (RNFL) were obtained from 4.5 mm × 4.5 mm optic nerve head (ONH) scans. Event-based OCT/OCTA progression was defined as decreases in ONH measurements exceeding test-retest variability on ≥2 consecutive visits. Visual field (VF) progression was defined as significant VF mean deviation worsening rates on ≥2 consecutive visits. Inter-instrument agreement on progression detection was compared using kappa(κ) statistics.
resultsAmong 147 eyes (89 participants), OCTA and OCT identified 33(22%) and 25(17%) progressors, respectively. They showed slight agreement (κ = 0.06), with 7(5%) eyes categorized as progressors by both. When incorporating both instruments, the rate of progressors identified increased to 34%. Similar agreement was observed in diagnosis- and severity-stratified analyses (κ < 0.10). Compared to progressors identified only by OCT, progressors identified only by OCTA tended to have thinner baseline RNFL and worse baseline VF. VF progression was identified in 11(7%) eyes. OCT and VF showed fair agreement (κ = 0.26), with 6(4%) eyes categorized as progressors by both. OCTA and VF showed slight agreement (κ = 0.08), with 4(3%) eyes categorized as progressors by both.
conclusionsOCT and OCTA showed limited agreement on event-based progression detection, with OCT showing better agreement with VF. Both OCT and OCTA detected more progressors than VF. OCT and OCTA may provide valuable, yet different and complementary, information about glaucoma progression.
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