ArticleBMC psychiatry2023
Depression severity mediates stigma and quality of life in clinically stable people with schizophrenia in rural China.
Article in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- The Moderating Role of Social Functioning in the Relationship Between Stigma and Quality of Life in Rural Chinese Patients with Schizophrenia: A Cross-Sectional Study.Neuropsychiatric disease and treatment · 2026Article
- Association between social support and quality of life in community-dwelling schizophrenics: the mediating roles of anxiety and depression symptoms.Health and quality of life outcomes · 2025Article
- Global burden and prediction study of schizophrenia 1990-2030: comparison with China.BMC psychiatry · 2025Article
- Mental health literacy and the stigmatisation and discrimination of individuals affected by mental illnesses in China: a scoping review.The Lancet regional health. Western Pacific · 2025Review
- [Association between stigma and quality of life in community-dwelling patients with schizophrenia: Multiple mediating roles of anxiety and depression symptoms].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- Parallel Mediating Effects of Sleep Quality, Psychological Distress, and Self-Stigma in the Associations Between Long COVID Symptoms and Quality of Life Among Taiwanese Individuals With Mental Health Illness.Brain and behavior · 2024Article
- Article
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10 authors.
Funding
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Abstract
backgroundDepressive symptoms associated with schizophrenia are closely related to stigma and quality of life(QOL). There is, however, no thorough research on the connection between the three. This study sought to investigate the possible factors influencing depressive symptoms in people with schizophrenia (PWS) in rural Chaohu, China, and to further explore the role of depression severity in stigma and lifestyle quality.
methodsEight hundred twenty-one schizophrenia patients accomplished the entire scale, including the 9-item Patient Health Questionnaire (PHQ-9), the Social Impact Scale (SIS), and the World Health Organization on Quality of Life Brief Scale(WHOQOL-BREF). A straightforward mediation model was employed to determine if the intensity of the depression could act as a mediator between stigma and QOL.
resultsTwo hundred seventy-nine schizophrenia patients (34%) had depressive symptoms (PHQ ≥ 10), and 542 patients (66%) did not (PHQ < 10). Logistic regression showed that marital status, job status, physical exercise, standard of living, and stigma contributed to the depressed symptoms of schizophrenia. Depression severity partially mediated the effect between stigma and QOL, with a mediating effect of 48.3%.
conclusionsThis study discovered a significant incidence of depressed symptoms associated with schizophrenia, with depression severity serving as a mediator variable connecting stigma and QOL and partially moderating the association.
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