ArticleBMC oral health2023
Comparative evaluation of antimicrobial efficacy of different combinations of calcium hydroxide against Enterococcus faecalis.
Article in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Comparison of the antibacterial properties of Resin cements with and without the addition of nanoparticles: a systematic review.BMC oral health · 2024Pooled it
- Efficacy of electronic apex locators in comparison with intraoral radiographs in working length determination- a systematic review and meta-analysis.BMC oral health · 2024Pooled it
- Antibacterial efficacy of calcium hydroxide, polyantibiotic paste, andJournal of conservative dentistry and endodontics · 2026Article
- Comparative antimicrobial efficacy of three intracanal medicaments in an in vitro Enterococcus faecalis root canal infection model.BMC oral health · 2026Article
- Comparative antioxidant efficacy of D-Cateslytin combined with modified triple antibiotic paste and calcium hydroxide: anFrontiers in dental medicine · 2026Article
- Antimicrobial efficacy of blueM gel and calcium hydroxide against F. nucleatum and E. faecalis biofilm: an ex-vivo study.The Saudi dental journal · 2025Article
- Antimicrobial activity of Salvia spinosa against Enterococcus faecalis causing endodontic infections: an in-vitro, ex-vivo, and in-silico study.BMC complementary medicine and therapies · 2025Article
- Comparative evaluation of the effectiveness of various intracanal medicaments in eliminating Enterococcus faecalis from simulated internal resorption cavities.Scientific reports · 2025Article
- Synergistic antibacterial effect of ginsenoside Rh2 and calcium hydroxide on Enterococcus faecalis.Odontology · 2025Article
- Novel approaches on root canal disinfection methods againstJournal of oral microbiology · 2025Review
- Antimicrobial Efficacy of Intracanal Medicaments Incorporated With Nanoparticles in Primary Teeth: An In Vitro Study.TheScientificWorldJournal · 2025Article
- Review
- Nanoarchitectonics-Based Materials as a Promising Strategy in the Treatment of Endodontic Infections.Pharmaceutics · 2024Review
- Comparative evaluation of the antibacterial efficacy of two experimental calcium silicate-based intracanal medicaments: AnJournal of conservative dentistry and endodontics · 2024Article
- Dental pathologies of endodontic origin and subsequent bacterial involvement - a literature review.Germs · 2023Review
Corrections and comments
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Authors and funding
8 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe study aims to compare the synergistic antibacterial efficacy of different combinations of calcium hydroxide as an intracanal medicament against E. faecalis. MATERIAL AND
methodsThe current study included four hundred extracted human permanent mandibular premolar teeth. After complete chemo-mechanical preparation, the middle third of the root was sectioned using a rotary diamond disc and a total of 400 samples were obtained. The specimens were inoculated with E. faecalis for 21 days. After that, specimens were divided into five groups (n = 80) based on materials used for the disinfection of samples: Group I, calcium hydroxide alone; Group II, calcium hydroxide + 2% chlorhexidine gel; Group III, calcium hydroxide + 2% chitosan gel; Group IV, calcium hydroxide + 0.02% silver nanoparticle gel; Group V, calcium hydroxide + Bioactive glass S53P4. Dentin shavings from the apical third were obtained from the inner third of dentin were obtained using gates glidden no.1 to the apical depth, followed by no.2, 3, 4 and 5 analyzed for E. faecalis using the culture method. One-way analysis of variance (ANOVA) was used for data analysis, followed by post-hoc Tukey's test for multiple comparisons of means to check the difference in bacterial inhibition between the groups.
resultsANOVA results revealed a significant reduction of bacterial counts in all the groups compared (p < 0.001). Intergroup comparison showed maximum bacterial reduction (p < 0.001) with calcium hydroxide + bioactive glass S53P4 compared with other groups.
conclusionSynergistic effect of calcium hydroxide showed better bacterial reduction compared to calcium hydroxide alone. Among the combinations evaluated, calcium hydroxide with bioactive glass, found to be most effective compared to other groups.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.