Evidence map›Paper›PMID 37950776›Full record

Trial reportJournal of autism and developmental disorders2024

Comparing the Effectiveness of Physical Exercise Intervention and Melatonin Supplement in Improving Sleep Quality in Children with ASD.

Andy C Y Tse, Paul H Lee, Cindy H P Sit, Eric Tsz-Chun Poon, F Sun, Chi-Ling Pang, James C H Cheng

Abstract readRandomized Controlled TrialComparative Study
PubMed Publisher
In one paragraph

Trial report in Journal of autism and developmental disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andy C Y TseDepartment of Health and Physical Education, The Education University of Hong Kong, Rm D4-2/F-02, Block D4, 10 Lo Ping Road, Tai Po, N.T, Hong Kong, China. andytcy@eduhk.hk.
Paul H LeeClinical Trial Unit, University of Southampton, Southampton, UK.
Cindy H P SitDepartment of Sports Science and Physical Education, Chinese University of Hong Kong, Hong Kong, China.
Eric Tsz-Chun PoonDepartment of Sports Science and Physical Education, Chinese University of Hong Kong, Hong Kong, China.
F SunDepartment of Health and Physical Education, The Education University of Hong Kong, Rm D4-2/F-02, Block D4, 10 Lo Ping Road, Tai Po, N.T, Hong Kong, China.
Chi-Ling PangSchool of Education, John Hopkins University, Baltimore, USA.
James C H ChengDepartment of Paediatrics and Adolescent Health, United Christian Hospital, Hong Kong, China.

Funding

University Grants Committee 18616522
6 · The paper itself

Abstract

purposePrevious studies have demonstrated that physical exercise can modulate the endogenous melatonin level in children with autism spectrum disorder (ASD) and improve their sleep quality. However, it remains unclear whether physical exercise or melatonin supplement, or a combination of both, is more effective in improving sleep quality in this population. The purpose of this study is to answer this research question by comparing the effectiveness of three types of interventions (physical exercise vs. melatonin supplement or a combination of both) in improving sleep quality in children with ASD.

methodsSixty-two (62) children diagnosed with ASD were randomly assigned to one of four groups: cycling (n = 18), melatonin supplement (n = 14), a combination of both (n = 12), and placebo control group (n = 18). Four (4) sleep parameters (sleep efficiency, sleep onset latency, sleep duration, and wake after sleep onset) were assessed.

resultsThe results revealed a significant improvement in sleep efficiency, sleep onset latency, and sleep duration in all of the interventions, but not in the placebo control group. However, no significant group differences were found among the interventions (ps > .05).

conclusionOur findings suggest similar effectiveness of physical exercise and melatonin supplementation in improving sleep quality in children with ASD.

Indexed as

Autism Spectrum DisorderExerciseMelatoninSleep QualityChildChild, PreschoolCombined Modality TherapyDietary SupplementsExercise TherapyFemaleHumansMaleSleepSleep Wake DisordersTreatment OutcomeMelatoninAutismChildrenMelatonin SupplementPhysical ExerciseSleep

Identifiers

PMID37950776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.